Drawing on archival research and a new attention to literary form, Sion’s Muse argues that the religious poetry of the English Reformation decisively constituted new modes of devotional affect for laypeople. At the beginning of the English Reformation, the psalm translator Miles Coverdale wrote, “Would God that our minstrels had...
Economic inequality has reached historically high levels in both the United States and in the world. The research literature in sociology and political science has long shown that individuals tend to be very persistent in their views on the determinants of economic success, although these views may be formed on...
Neurodegenerative diseases (NDs) commonly involve the accumulation and aggregation of neurotoxic proteins that impair and ultimately destroy specific neurons. Considerable evidence from human and animal studies indicates that many NDs show disrupted circadian and sleep as symptoms. Yet little is known about the molecular mechanisms by which genes cause NDs...
Dystonia is a movement disorder characterized by involuntary and repetitive co-contractions of the agonist and antagonist muscles. Dystonia 6 (DYT6) is an autosomal dominant dystonia caused by loss of function mutations in the zinc finger transcription factor THAP1. I have generated Thap1 knock-out mice with a view to understanding its...
The Brink-Schwarz superparticle is a one-dimensional analogue of the Green-Schwarz superstring. In this thesis, we use the Batalin-Vilkovisky formalism to study the superparticle. After proving a vanishing result for its Batalin-Vilkovisky cohomology, we explain the sense in which the superparticle exhibits general covariance in the world-line. Using techniques from rational...
Spinal cord injury (SCI) is a devastating injury, which can be caused by motor vehicle accidents, violence, and non-traumatic causes. These injuries can leave patients with lifelong paralysis, as well as incontinence and life threatening autonomic dysreflexia. There is currently no FDA approved treatment for SCI. Spinal injury disrupts the...
Developing materials with comparable structural complexity and programmed hierarchy as those found in nature is a grand challenge in materials science. One way to synthesize soft materials with these complex architectures is to use bottom-up self-assembly of nanoscale building blocks, mimicking how organisms grow tissues with specific functions from peptides,...
This dissertation, titled “Empire of Ruins: France in Roman Africa, 1830-1900,” explores the relationship between French colonialism in Algeria and Tunisia and the study of Roman Africa in the nineteenth century. Its central argument is that the French study and use of Roman ruins produced a version of Roman history...
Pragmatic language, or the use of language in social contexts, is critical to developing meaningful social relationships and is a significant contributor to mental health. Autism spectrum disorder (ASD), fragile X syndrome (FXS) and Down syndrome (DS) are all genetically based neurodevelopmental disabilities characterized by deficits in pragmatic language, although...
Segregation of polydisperse granular materials remains to be a challenging problem in many industrial processes. However, most studies have focused either on bidisperse (two different particle size species) materials, which are not representative of most real mixtures, or on polydisperse materials in an idealized simple geometry. Additionally, most studies have...
In the first chapter I introduce the ideas that link selling information to surplus extraction. In my environment the seller may be uncertain about how much the buyer both has already learned before contracting with the seller (belief types) and is able to learn after contracting with the seller (information...
Heterogeneous catalysts based on metal oxides are of significant interest for many industrial chemical reactions. These catalysts, however, often suffer from ill-defined structures that preclude better understanding of the surface phenomena. Thus, structurally well-defined catalysts have received growing attention by making it feasible to understand the kinetics and reaction mechanisms....
Prenatal alcohol exposure is a global health concern. Despite guidelines advising against it, many women continue to drink throughout their pregnancies. Exposure to alcohol can have lifelong medical, social, emotional, and intellectual consequences on a developing fetus. Women in Uruguay have demonstrated consistently high self-reported alcohol consumption during pregnancy, but...
The three studies in this project investigate a selected number of youth protective factors and caregiver parenting skills with reducing the risk of justice involvement for youth involved in the child welfare system without a prior history of justice involvement. All three studies used child welfare administrative data, and the...
Built from non-covalent interactions, supramolecular biomaterials are highly dynamic and tunable, and recent work has shown that they are uniquely capable of mimicking functional biological structures. In this work, supramolecular biomaterials built from self-assembling peptide amphiphiles (PA) were investigated with the goal of precisely tuning their cohesive interactions to optimize...
Clientelism has been largely defined as an electoral strategy in which politicians distribute resources to voters to gather their support. This study proposes a new framework to understand clientelism by inverting the perspective of this practice, focusing on voters rather than politicians. This study proposes that clientelism should be understood...
Individuals following a stroke suffer from a host of movement impairments that affect the upper extremity. Hand use is often significantly compromised, especially in individuals with more severe impairments, which makes it difficult for individuals to participate in activities of daily living. One of the major goals of rehabilitation is...
This dissertation has two main aims. The first is to show that relying on the testimony of others is not as “epistemically special” as many epistemologists have made it out to be. More specifically, I argue that relying on someone’s testimony neither provides us with a non-evidential, epistemic reason to...
This dissertation addresses the property of amenability of discrete groups and their actions. In Chapter 2, following the introduction, all necessary definitions are given to introduce amenable groups, elementary amenable groups, random walks, topological full groups, Thompson's group $F$ and to show connections between them. The chapter also briefly covers...
Young children can sometimes acquire new vocabulary words—even property terms—through indirect learning (e.g. Carey & Bartlett, 1978). We explore two factors that contribute to this ability—perceptual alignment and linguistic contrast. We propose that spontaneous comparison processes lead children to notice key commonalities and differences that facilitate indirect property word learning....
This dissertation traces the historical development of diasporic Filipino American activism after the watershed 1965 Immigration and Nationality Act and during the military dictatorship of Ferdinand E. Marcos in the Philippines. Using multi-country archival research and approximately sixty oral history interviews, it analyzes labor, student, anti-dictatorship, and human rights activists...
Intestinal immunity is a critical contributor to host health. The immune system in the intestine maintains both defense against pathogens and homeostasis of intestinal tissue, which is exposed to environmental influences, including microbes and ingested foods. Proper regulation of the immune response is required to prevent damage to the host....
This dissertation explores our understanding of corporate credit ratings. In the first chapter I examine the issue of split ratings. S&P and Moody’s often differ in their initial ratings at bond issuance, producing what is referred to as a split rating. The consensus view in the literature and in practice...
Additive manufacturing is a promising process that has the capability to build components with complex geometries for structural and biomedical applications. Due to the rapid and localized directional solidification of molten metallic alloys, unique phase transformations occur at the melt pool that can provide for components with greater strength and...
This thesis describes a series of fundamental studies that address the role of electrostatic interactions in modulating i) the permeability of the ligand shell of a colloidal quantum dot (QD) to an anionic redox probe; ii) the resulting yield of photoinduced electron exchange within the QD ‒ redox probe complex;...
Knee injury causes a loss of stability in the joint and frequently leads to secondary degeneration of the cartilage in the months and years after injury, which can further impair joint function and cause pain and disability. Moreover, the secondary damage to the joint appears to be worse for females...
As national, state, and local educational leaders grapple with how to effectively address the needs of gender-expansive students, more research is needed to inform policy. Gender-expansive youth experience high rates of chronic social stressors such as victimization, discrimination, and rejection. These stressors have academic, mental and physical health consequences; however,...
Neural networks have revolutionized the field of computer vision since they provide solutions to a number of previously unsolved problems and achieve promising performance both in terms of accuracy and computational efficiency. It has increasingly become recognized as providing high performance for applications as diverse as image classification, object detection,...
This dissertation examines connections between North and South Korean art during the late Cold War period. Despite the radical social and political differences between the two countries, in the 1980s and early 1990s conspicuous connections emerged between the work of state-sponsored North Korean artists and South Korean artists associated with...
This dissertation argues that black women’s literature on black-white multiraciality critiques public debates that celebrate the racially ambiguous multiracial child as the solution to racial conflict. Under this framework, this project investigates the popularization of multiracial identity in late 20th and 21st century United States, United Kingdom, and Jamaica, and...
In the early part of the 20th Century, the Communist Party of the Soviet Union implemented a program of rapid industrialization under the slogan, “the conquest of nature by man.” Ambitious engineering projects such as the construction of the White Sea-Baltic Canal and the Northern river reversal sought to restructure...
Oxide/aqueous and metal/metal oxide interfaces are essential for environmental remediation, catalysis, and corrosion inhibition, in addition to their potential implementation as energy transducers, consumer electronics, and coating products. While these interfaces are critically important, they are difficult to access experimentally under aqueous flow conditions. This thesis describes results obtained with...
This dissertation is a social and cultural history of the body and the beauty industry in the Japanese Empire from 1868 to 1945. The emphasis is on the thoughts and actions of state and private actors such as doctors and the first generation of Japanese cosmetic product developers. When these...
Rhythmic fluctuations of electrical activity in the brain provide insights into the proposed mechanism by which we encode experiences and then maintain, forget, modify, and retrieve them. Yet there is still much to learn about how neural oscillations relate to memory function. The purpose of this research is to discover...
The fields of metabolic engineering and synthetic biology have emerged in recent years with the heavily overlapping goals of sustainable bioproduction of chemical goods and predictable and precise engineering of biological function.1 However, efforts to reach commercially relevant titers have stalled.2 Many challenges arise during optimization of each production platform,...
Computer simulation experiments are commonly used as an inexpensive alternative to real-world experiments to form a metamodel that approximates the input-output relationship of the real-world experiment. The metamodel can be useful for decision making and making predictions for inputs that have not been evaluated yet since it can be evaluated...
We start from a set of users communicating over a Gaussian multiple access wire-tap channel with confidential messages, where users attempt to transmit private messages to a legitimate receiver in the presence of an eavesdropper. While prior work focused on the case where the users were cooperative, we assume that...
Solid Oxide Fuel Cells (SOFCs) are a low-emission, efficient and fuel flexible energy conversion devices, which have been extensively applied in electricity generation systems. Moreover, it can also be operated in electrolysis mode as Solid Oxide Electrolysis Cell (SOEC) or Reversible Solid Oxide Cell (ReSOC) for intermittent renewable energy storage....
One method of cancer treatment is to thermally ablate (destroy) tumor masses using heat caused by electric current, or Joule heating. This particular modality is called radiofrequency ablation (RFA), due to the use of electric currents in the 100 kHz to 800 kHz frequency range. Computationally, RFA is simulated as...
When attached to another species (e.g. a nanoparticle), the sequence specificity of DNA can be repurposed to program interactions between such entities and to direct their formation into ordered structures. The research presented in this thesis aims to push the boundaries of structures that can be made via this approach....
Rapid changes in global climate are pushing nations to reduce CO2 emissions and adopt clean energy technologies for renewable energy generation and storage. As wind and solar are implemented worldwide, a commensurate response in energy storage will need to be installed to meet fluctuations in peak energy demands and generation...
This thesis focuses on the application of neural networks to three types of classification tasks, each work with its own chapter. The objective of the first work is to take advantage of deep neural networks in order to make next day crime count predictions in a fine-grain city partition. We...
Harnessing the metabolic potential of methanotrophic bacteria is a compelling strategy for the bioremediation of environmentally harmful methane gas. Methanotrophs can activate a 105 kcal/mol C-H bond in methane at ambient conditions using metalloenzymes called methane monooxygenases (MMOs). Particulate methane monooxygenase (pMMO) is a copper-dependent, membrane-bound enzyme that is the...
Selective attention enables people to focus on a small number of objects, features, or events with good resolution. Sometimes attention may also be less selective and distributed across numerous items, which allows more information to be processed at a lower resolution. The degree to which attention is more or less...
Abstract This dissertation aims to understand how the domestic high courts in Latin America rely on the jurisprudence of the Inter-American Court of Human Rights. The “relationship between courts” is a phenomenon that happens in domestic and international politics when domestic high courts start to resist or follow international jurisprudence....
The spatial autoregressive model has been widely applied in science, in areas such as economics, public finance, political science, agricultural economics, environmental studies and transportation analyses. The classical spatial autoregressive model is a linear model for describing spatial correlation. In this work, we expand the classical model to include time...
Biogenic secondary organic aerosol (SOA) particles, produced by forest ecosystems across the globe, are principal, yet poorly understood constituents in the climate system. These atmospheric particles form when biogenic volatile organic compounds (BVOCs) react with atmospheric oxidants, leading to increasingly lower volatility oxidation products that partition into the condensed phase...
Molecules and materials featuring unpaired electrons are fundamental elements of modern energy, device, and imaging technologies. The high sensitivity of electronic spins to their surroundings renders these compounds further attractive as environmental sensors. In order to successfully realize these applications, the electronic spins must be precisely controlled. One promising strategy...
Demand Response (DR) is an approach that allows electricity users to actively participate in keeping supply-demand balance in power systems, or its future version, smart grid, in order to increase the system efficiency, lower consumers' electricity bills, and thus improve social welfare. To encourage users' participation in DR, a time-varying...
Understanding the complex genome-phenome associations behind human complex traits will be a primary focus for the practice of precision medicine in the future. Identifying the genetic variants that contribute to the inter- and intra- phenotypic variations of individuals, elucidating pleiotropic architecture of common complex traits, and demonstrating how personal biomedical...
The development of heavy metal semiconductors is a growing field of interest for their application in photovoltaics, light emission, and radiation detection. This is due to their robust ability to convert incident photons of visible wavelength and high energy into charge current while remaining stable, optimizable, and readily synthesizable. As...
With the ability to rapidly screen and manipulate genomes, the in depth study of the functional actors of biology—metabolites and proteins—is necessary to understand complex biochemistry in developmental and disease states. The analytical processes by which biological information is gained from metabolomics and proteomics experiments must also evolve with our...
Burkitt lymphoma (BL) is a B cell cancer that develops primarily in children and is associated with Epstein-Barr virus (EBV). The EBV latent membrane protein 2A (LMP2A) drives BL in part by providing constitutively active pro-survival signaling. A double transgenic mouse model of BL expressing LMP2A and the oncogene MYC...
In this thesis I focus on two topics: planet-disk interaction and solar convection. These two seemingly separate topics are connected via a similar separation of timescales. Planets excite spiral waves in their disks on fast timescales compared to the time for the disk to viscously adjust to the angular momentum...
By showing how the heteroglot and tentative nature of medieval normative worlds furnishes a salutary alternative to contemporary epistemologies of the globe, this dissertation contributes to critical theory that deconstructs the globe as a modern concept defined as a transparent space of circulation and exchange. While studies of the global...
To survive, animals, including human beings, have developed an amazing ability to learn the constantly changing environment. Specifically, detecting specific odorants in a noisy, variable background is crucial for finding food and water, mating, and avoiding potential dangers. For this purpose, rodents have developed an olfactory system that is powerful...
This dissertation aims to redefine the concept of pain as it appears in literary studies and demonstrate how the new definition garners insight into the interwovenness of literature and physiology in the mid-eighteenth century. It challenges the claim that pain is opposed to language by adopting a new materialist concept...
Modeling the mechanical performance of metal produced with additive manufacturing (AM) has proven to be a challenging task. In the as-built state, these materials have been shown to exhibit strong heterogeneity and anisotropy. Even after post-processing, such as heat treatment or hot isostatic pressing and depending on the alloy, some...
Molecules are highly social: they recognize one another and form bonds with those they are attracted to and repel those they are not. Some molecules establish strong bonds, while others form weak, transient associations. These interactions are ubiquitous in Nature and are integral to life. For at the basis of...
The application of formal multilayer networks (MLNs)—networks which contain multiple types of relationships, data types, or other additional features of complexity and connectivity—has recently become popular in many fields. Areas of study ranging from social science to biology have utilized MLNs to explore, describe, and analyze interconnected complex systems. MLNs...
Metal Additive manufacturing (AM) processes build 3D objects by heating and consolidating material in a point-by-point manner. Unlike traditional manufacturing methods, AM allows the material properties of each point in the build to vary by controlling process conditions locally. The process parameters can be considered as inputs to the AM...
This dissertation describes modifications to the surface of colloidal semiconductor quantum dots (QDs) to improve their use as photocatalysts for charge transfer reactions. The surface atoms and ligands of these nanoparticles can interfere with direct charge transfer to a reagent by inhibiting binding, forming trap states, or acting as competitive...
Understanding the outcomes of interactions from assessing shoot traits has practical applications and has elucidated major ecological patterns. Roots and shoots differ in their functions and can differ in responses to abiotic and biotic stimuli. And while roots are more difficult to characterize because they tangle and are embedded in...
Label-free assays, and particularly those based on the combination of mass spectroscopy with surface chemistries, enable high-throughput experiments of a broad range of reactions. However, these methods can still require the incorporation of functional groups that allow immobilization of reactants and products to surfaces prior to analysis. In this thesis,...
In this dissertation I leverage new data from the global music recording industry to study the social foundations of creativity and the relationship between product novelty, gender, and commercial success. In Chapter 1, I investigate how different kinds of social connection influence the creation of novel cultural products. Using data...
This thesis explains the works that have been completed towards the Ph.D. thesis of the author and discusses the conclusions derived from the results, as well as what future holds for stress-related mobile health research. Main focus of the thesis is use of wearable sensors to understand physiological manifestation of...
Understanding structure-property relationships for polymer nanocomposites is one of the primary challenges in discovering new, light weight, multifunctional advanced materials. Polymer nanocomposites are a class of advanced materials comprised of soft polymer matrix and nano-filler inclusions. While it has been found qualitatively that enhancements of material properties could be achieved...
A growing body of research analyzes how corporate social responsibility programs are used to absorb and neutralize the social criticisms coming from social and environmental movements and to superficially respond to the ensuing new regulations. If companies have powerful tools to resist changes and blunt the meaning of the law,...
Maneuvering your limbs requires both accurate commands for how to move, and accurate feedback of their true movements. Conventional prosthetic arms currently lack this sense of proprioceptive feedback, which can make daily tasks difficult without close visual monitoring. Although studies have successfully provided artificial proprioceptive feedback to improve control, this...
Deep learning is a new area of machine learning research that allows deep neural networks composed of multiple processing layers to learn representations of data with multiple levels of abstraction. Deep learning has helped in achieving the objective of pushing machine learning closer to one of its original goals of...
Neurons are sensitive to the mechanical properties of their environment and show better growth, survival and differentiation when they are cultured in soft environments with mechanical properties similar to those of the brain compared to other tissues. Within the central nervous system (CNS), there is also a range of mechanical...
Desmosomes, complex structures found at intercellular junctions, are important for the development, structural integrity, and immune barrier of the skin. Extracellular components of the desmosome connect neighboring cells and intracellular interactions amongst cadherin, armadillo, and plakin proteins anchor the desmosome to intermediate filaments. Beyond their canonical role as “spot welds”...
With the growing size of networks and datasets and the lack of centralized access to information, distributed control and optimization become inevitable. In the first part of this thesis, we develop an asynchronous Newton-based distributed optimization algorithm and analyze its convergence properties. Our algorithm benefits from the fast convergence properties...
Organic solar cells (OSC) are a next generation solar energy technology that offers the advantages of scalable fabrication, light weight, flexibility, and earth-abundant starting materials. Despite tremendous advances in OSC power conversion efficiency (PCE) over the last decade, active layer material selection and optimization is still largely empirical. In order...
Hollow biopsy needles are widely adopted medical devices for the removal of biological tissue to better identify a lesion or an abnormality observed through a physical exam or a radiology scan. These procedures can provide significantly more information than most medical tests, and they are usually performed on dermis layers,...
Low-dimensional materials have emerged as a promising platform for ultrathin electronic and optoelectronic devices. The span of electronic properties covers the spectrum from metallic through small and medium bandgap semiconductors to large bandgap insulators, providing all the necessary components to fabricate a variety of devices. Compared to bulk-semiconductor based devices,...
The active participation of external entities in the design and manufacturing flow has produced numerous hardware security issues. Among all the hardware security problems, piracy and overproduction are likely to be the most ubiquitous and expensive ones. Most leading-edge design houses have outsourced their fabrication to the offshore foundries for...
The goal of the work reported here was to answer two important questions with regards to LTVV use for patients with ARDS: 1) How do we measure adoption? and 2) What are the drivers of provider adoption? To this end, I have demonstrated the influence of patient height, hypoxemia severity,...
Researchers and educators have argued that productive learning may occur when young people have freedom to organize their activity based on their own interests and concerns. Schools increasingly provide “makerspaces” that allow students to design and build objects and technical devices of their choosing, and researchers have developed in-school programs...
This dissertation studies three topics in 19th and early 20th century economic history. Chapter 1 studies the causes behind low inter-regional migration from the American North to the South prior to the Civil War. Chapters 2 and 3 focus on topics in the economic history of Egyptian agriculture. Chapter 2...
Animals must establish the correct form during development. Regeneration is a process by which some animals reestablish their form following injury. This process requires both the generation of new missing cells after injury, and information to pattern new cells to reestablish the correct form. Planarian flatworms have an almost unlimited...
Techniques for achieving complete quantum control over atoms have been developed and perfected over the past four decades with great success. This work has led to multiple Nobel prizes and has been the catalyst for rapid advances in a broad array of research fields. A natural progression forward is to...
The ribosome, the cell’s machine for synthesizing proteins, can be thought of as the chef of the cell. Just as a chef reads a recipe and combines ingredients to create a dish, the ribosome reads cellular instructions and connects building block molecules (amino acids) to construct proteins. Like the final...
Chapter 1: Telomerase is a ribonucleoprotein enzyme that counteracts the shortening of telomeres by catalyzing the addition of nucleotides to the 3’ ends of chromosomes, resulting in telomerase inhibition attracting interest as a strategy for cancer. Telomerase has also been implicated in other tumorigenic pathways such as DNA damage repair,...
Foreign currency debt has led to many crises in emerging markets. In the past decade, firms in emerging economies have drastically increased their foreign currency borrowing, making them significantly exposed to depreciation shocks. To reduce their exposure to external shocks, central banks have increased their use of regulation, such as...
Superalloys strengthened by γ′(L12)-precipitates in γ(f.c.c.)-matrix exhibit superior high temperature mechanical properties and environmental resistance over long periods of operation, making them ideal candidates for aerospace and energy conversion applications. The emerging class of superalloys based on Co-Al-W ternary system was identified with a melting temperature 50-100 ˚C higher than...
Self-Assembled Monolayers for MALDI-TOF Mass Spectrometry (SAMDI-MS) is a technique that combines self-assembling molecules of alkane disulfides on gold and MALDI-TOF mass spectrometry. By using well-defined monolayers with functionalizations that both prevent non-specific adsorption onto the surface and presents immobilization handles, it is possible to pull out analytes of interest,...
During influenza A virus (IAV) infection, severe lung injury and death result from an exuberant host inflammatory response, or “cytokine storm”, orchestrated by pulmonary epithelial cells. The linear ubiquitin assembly complex (LUBAC), composed of SHARPIN, HOIL-1L and HOIP, is a critical regulator of NF-κB-dependent inflammation. To determine the impact of...
The importance of concern for others in the lives of emerging adults has been underestimated by emerging adult theory. In this set of studies, I explore emerging adults’ concern for others in the higher education context. I use three different samples, a group of 10 Latino emerging adults working to...
Atrial fibrillation (AF) is the most common arrhythmia in adults in the United States. Despite its prevalence, the etiology of AF and its adverse effects are not completely understood, which has made treatment of AF difficult. However, left atrial (LA) fibrosis is associated with worsening and propagating AF. Additionally, research...
The histone methyltransferase DOT1L methylates lysine 79 (K79) on histone H3 and is implicated in active transcription. Here we show that DOT1L is overexpressed in Prostate cancer (PCa) and is associated with poor clinical outcome. Genetic and chemical inhibition of DOT1L selectively impaired viability of androgen receptor (AR)-signaling competent PCa...
This work is composed of two separate projects that contribute to the field’s understanding of Neisseria gonorrhoeae genetics and physiology. First, I showed that N. gonorrhoeae mounts a substantial transcriptional program in response to hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during infection. We measured which strain...
The continued existence and use of chemical warfare agents (CWAs) have necessitated the development of materials which can safely and efficiently decontaminate these toxic chemicals in an environmentally benign fashion. Among the most prevalent CWAs, nerve agents (sarin, VX) and blistering agents (sulfur mustard [HD]) are considered the most toxic...
The viscoelastic properties of microbial biofilms have attracted great interests in recent years due to the ubiquity of biofilms and their wide range of industrial and municipal applications causing tremendous societal impacts. Biofilms are predominantly architected by extracellular polymeric substances (EPS) matrices composed of bacterial cells and biopolymers secreted by...
In this dissertation, we study models and methods to address uncertainties that can vary in optimization problems. Robust optimization is a popular approach for optimization under uncertainty, especially if limited information is available about the distribution of the uncertainty. It models the uncertainty through sets and finds a robust optimal...
Nucleic acid drugs promise to revolutionize the development of therapeutics. They offer a platform for digital medicine, where systematic changes to the nucleic acid sequence can be utilized to target the entire human genome. However, nucleic acids suffer from a number of drawbacks, such as negligible cellular uptake and rapid...
Mineral inclusions in diamond, brought to the surface through kimberlitic eruptions, provide a unique glimpse into the geochemical inner workings of Earth’s deep interior. Diamonds source a wide range of depths in the mantle. While most diamonds originate from the upper 200 km of the Earth’s mantle, aptly called super-deep...
Episodic memory provides a means by which we reflect on the past, make decisions about the future, and form a learned identity. Episodic memory depends on the hippocampus as well as on the distributed set of regions that form a hippocampal-cortical network (HCN), including medial prefrontal, posterior cingulate, and medial...
Skeletal muscle is one of the most abundant tissues in the body and makes up over 40% of the total body mass. It is important for mobility and posture maintenance as well as plays a central role in whole body metabolism. Skeletal muscle is made up of bundles of muscle...
Dilute Al-Sc-Zr-Si-based aluminum alloys retain their strength for long periods of time at elevated temperatures due to a dispersion of nanometric, coherent, and coarsening-resistant Al3(Sc,Zr) (L12 structure) nanoprecipitates that are formed upon aging. These alloys are attractive for replacement of dense steels and costly Ti alloys in the 250–400 °C...