This dissertation starts with the question of what the global resurgence of authoritarianism means for the welfare states affected by it. The inadequacies of the dominant partisan and institutionalist paradigms within the welfare state literature suggest, however, that a new paradigm for understanding welfare state development is necessary to answer...
Though they lived a century apart and wrote in starkly disparate historical, cultural, and literary contexts, Russian poets Aleksandr Pushkin and Vladimir Mayakovsky were both victims of the posthumous processes of bureaucratization and monumentalization at the hands of the Soviet regime. Their biographies, politics, and poetry were sanitized and manipulated...
Dynamic covalent chemistry (DCC) combines the strength and directionality of covalent bonds with the reversibility of supramolecular interactions. The formation and stability of these bonds are typically regulated by parameters such as temperature, pH, concentration, catalyst loading and light. Light is an exceptionally powerful stimulus because it can be applied...
Stimulus generalization is a critical mechanism for facilitating behavioral flexibility. Generalization allows the brain to reduce computational demands that would otherwise be necessary to create unique representations for each and every encounter while allowing the ability to deal with the complexity of real-world situations. Stimulus generalization is a fundamental cognitive...
With the rapid advancement of machine learning techniques (in particular deep neural networks), computer vision applications have shown great promises in a variety of domains for intelligent cyber-physical systems (CPSs), such as autonomous driving, medical imaging, and vision-based robotic systems. However, while many vision applications provide great on-paper performance, their...
Crystalline and Framework materials make up a broad class of structures which are known for their precise and regular nature. Because these materials have predictable structures and compositions to their networks, they are widely used for several applications including electronics, optics, and catalysis. While these materials are of particular interest,...
This dissertation interrogates the quality of sincerity as it appears throughout John Locke’s work on religious toleration and Christian theology. Sincerity, and the framework it provides, offers a means to draw together his political and theological works, as well as to appreciate both his radical potentialities and conservative impulses. The...
Part I:Current approaches to synthesize π-conjugated polymers are dominated by thermally driven, transition-metal-mediated reactions. Herein we7 show that electron-deficient Grignard monomers readily polymerize under visible-light irradiation at room temperature in the absence of a catalyst. The product distribution can be tuned by the wavelength of irradiation based on the absorption...
Cobalt(III) Schiff-base complexes (Co(III)-sb) have been utilized in the literature as antibacterial, antiviral, and inhibitory agents. Recent work has utilized their ability to displace endogenous metals from metalloproteins that exhibit aberrant gain of function pathologies in human disease. Specifically, in this dissertation Co(III)-sb has been applied as inhibitors of pathogenic...
Travel time is a key aspect of capturing and evaluating the operational performance and service quality of transportation systems, and travel time improvement is a common objective for travelers, service providers, transportation practitioners and agencies. However, the reliability of travel times, including the probability of unexpected delays, is an important...
At its core, the purpose of microscopy is to make objects and their underlying structures visible under high magnification. With the remarkable progress of electron microscopy, the sub-micron “high” magnification of light microscopy has been completely refashioned to encompass subatomic length scales. Unfortunately, higher-magnification does little to negate existing interpretability...
Plasmonic nanoparticles have very large absorption cross sections and can concentrate the local density of photon states on the nano scale. When they are coupled to molecules or semiconductor nanocrystals and form different hybrid nanostructures, various light-matter interaction processes can be significantly enhanced or manipulated, including optical responses like fluorescence...
As fourth-generation synchrotron x-ray sources start to come online, they bring with them the promise of increased imaging speed and resolution for current imaging modalities, while enabling entirely new ones. Employing the increased brightness at hard x-ray energies begins with having efficient focusing optics in place. Zone plates are popular...
Recently, machine learning and deep learning, which have made many theoretical and empir- ical breakthroughs and is widely applied in various fields, attract a great number of researchers and practitioners. They have become one of the most popular research directions and plays a sig- nificant role in many fields, such...
Fluctuations are ubiquitous in physics.For a system close to a phase transition, the order parameter fluctuations are strong.
In this thesis we study the pair fluctuations in liquid 3He when it is close to the superfluid phase transition.
Liquid 3He is a neutral Fermi liquid, which allows zero sound to...
The purpose of my thesis research has been to understand the formation of mitotic chromosome structure by using chromosome micromanipulation. Folding mitotic chromosomes from their loose interphase form into their individualized, compacted form is required for easy handling of the chromosomes for cell division. This process is facilitated by several...
This dissertation describes three studies which develop a deeper understanding of both failure and performance in human service referral networks focusing on veterans. It draws on theories across network science, public administration, organizational communication, and technology design to explore three major questions: 1) how stakeholders in veteran care networks define...
In the past decade, the e-hail service provided by transportation network companies (TNCs) gained popularity in major cities around the world. By allowing passengers to virtually “hail” vehicles on mobile phones, e-hail has revolutionized the matching process in ride-hail, drastically reducing the existing search friction. However, previous studies found the...
Creating sustainable and clean sources of energy is an outstanding problem of importance for the current generation of scientists to solve. Organic photovoltaics (OPVs) are a promising renewable energy source but require improvements to their architectures and better fundamental understanding of the effects of organic chromophore morphology on the resulting...
Part I - Experimental Studies of Spin Waves in a Micrometer-Thick Yttrium Iron Garnet filmAn investigation of spin wave dispersion in a micrometer-thick ferrimagnetic yttrium iron garnet (YIG) film has been conducted in various regimes. In the linear excitation regime, the dispersion of spin waves was characterized in an yttrium...
Over the past decade, wearables have become pervasive in our lives. Healthcare wearables like a smartwatch continuously monitor personal health status and provide personalized feedback to motivate progress towards medically recommended goals. While present set of on-body electronics empowers users to visualize health status outside of clinic spaces, its traditionally...
How well do Probabilistic Seismic Hazard Analysis (PSHA) maps forecast ground shaking due to earthquakes? This question is central to ensuring the safety, security, and economic well-being of citizens. PSHA maps are an important product for users including seismologists, engineers, insurers, and policymakers. PSHA, which has been used worldwide for...
Parshin's conjecture expects that the higher algebraic $K$-groups of smooth projective varieties over a finite field are torsion. In this thesis we prove that with the assumption of finite generation of higher \'etale algebraic $K$-theory of smooth projective varieties over a finite field, one can reduce Parshin's conjecture to the...
Electrochemical devices play a vital role in the efforts towards a sustainable green future. Solid acid based electrochemical cells, employing super protonic CsH2PO4 (CDP) as the electrolyte component, offer unique application advantages due to their operability at intermediate temperatures 250°C. At these temperatures, one can achieve improved reaction kinetics over...
The eukaryotic genome is packaged into chromatin. The nucleosome, the basic unit of chromatin, is composed of DNA coiled around a histone octamer. Histones are among the longest-lived protein species in mammalian cells, due to their thermodynamic stability and their associations with DNA and histone chaperones. Histone metabolism plays an...
A greater number of strategies in one’s coping repertoire (i.e., the number of diverse strategies used across stressors or use habitually across several situations) may be beneficial and a precursor to coping flexibly across situations (Bonnano & Burton, 2013). Indeed, previous studies have demonstrated a benefit of having larger number...
To combat the rise of antibiotic-resistant pathogens in clinical settings, it is necessary to understand which environments and conditions select for antibiotic resistance. Analysis of environments hypothesized to select for antibiotic resistance has been revolutionized by metagenomic sequencing. The metagenomic pool of DNA sequences can be probed in silico using...
In recent decades, mass loss from glaciers and ice caps (GICs) worldwide has accelerated, contributing significantly to the observed sea–level rise. Their continued melt is also expected to alter local hydrological systems, affecting freshwater availability and quality. Despite these problematic impacts, little is known about GIC variations prior to the...
There is more responsibility on heaven and earth than dreamt of in most philosophy. This dissertation explores three debates in three sub-fields of philosophy, highlighting in each responsibilities agents find themselves with whether they like it or not. In the chapter Trust Logic, Not Tortoises, I propose an answer to...
Successful restoration depends on the establishment and survival of selected species, and sowing seed is the most cost-effective method to ensuring a successful restoration. Generally, a locally sourced seed is thought to be better adapted to local environmental conditions and, therefore, more likely to thrive. In addition, a local seed...
The study of solid-state organic chromophores has been soaring in the last decade owing to their wide applications in organic photovoltaics. These organic chromophores can absorb light in the visible region and form free charge carriers with proper design in molecular structure and device fabrication. In solid state, chromophores are...
The dentate gyrus is the first region for information processing within the classic hippocampal trisynaptic circuit, and this position makes it an important structure for the formation of associative memories. The dentate gyrus contains two major types of excitatory neurons: granule cells and mossy cells. While previous work has shown...
This dissertation examines how eighteenth-century ethics were reimagined by Enlightenment-era and Romantic women writes to better afford the grounds for political revolution and responsive reform. Whereas Adam Smith’s theatrical model of sympathy casts individuals in the passive role of spectators who feel deeply but are not necessarily moved to act,...
Peptides consists of a series of amino acids connected via an amide type of covalent chemical bond. A diverse field of applications such as biosensors,2 catalysis,4 and biomedicine6 include the oligomeric forms of peptides due to their genuine features comparing to other biomacromolecules. Particularly, peptides in the field of biomedical...
Nanocarriers, structures with at least one dimension on the nanoscale (1-1000 nm), have been engineered for delivery of various cargoes. The shape and flexibility of nanocarriers are important parameters that influence their biological performance. Self-assembling polymeric filamentous nanocarriers, known as filomicelles (FM), are of great interest to nanomedicine due to...
Ovulation is the process by which an ovulatory follicle releases a mature egg and is essential for fertility and maintaining female reproductive cycle. Understanding the mechanisms of ovulation have implications for the development of non-hormonal contraceptives and treatments of anovulatory diseases. We developed a 3D alginate encapsulated in vitro follicle...
Receptor for activated C kinase 1 (RACK1) is a core small (40S) ribosomal subunit protein whose structure is highly conserved among eukaryotes apart from a C-terminal extended loop. We previously showed that a poxvirus kinase phosphorylates this flexible loop in human RACK1, mimicking endogenous negative charge in plant RACK1 to...
Nanocarriers are drug delivery vehicles that have at least one dimension at the nanoscale (10-9 m). Engineering the nanocarrier surface is a strategy for targeting drug delivery to specific cell types to enhance efficacy and minimize side effects. A useful analogy is to consider how the chassis of an automotive...
Vaccines, such as those against smallpox virus, polio virus, and yellow fever virus, have saved millions of lives. However, many infectious diseases, such as HIV-1, still lack a preventive vaccine. In addition, various vaccines, such as those against Influenza and SARS-CoV-2 require boosters and may not confer 100% lifelong protection...
Cyclic loading, from earthquake, has caused the instability and failure of slopes composed of sensitive clays. During the 1964 9.2 moment magnitude (M) earthquake in Anchorage, Alaska, several slopes comprised of Bootlegger Cove Formation (BCF) clays failed during the strong seismic motion. Some researchers have proposed the use of residual...
The cuprate superconductor HgBa$_2$CuO$_{4+\delta}$ (Hg1201) has one of the simplest physical structures of the cuprates making it an ideal candidate for nuclear magnetic resonance (NMR) measurements. Here we discuss our NMR experiments aimed at studying the mixed state of two under-doped single crystal Hg1201 samples at high magnetic fields.
This dissertation reports on a 16-week ethnographic study of politicized caring within a museum-based tinkering program for high school students called the FabYouth program. Drawing on a data set that includes 16 field notes, 785.83 minutes (about 13.1 hours) of ethnographic audio-video recordings, 280 photographs, and ten student interviews, I...
Realizing electromagnetic metamaterials which operate in the optical regime requires creating precise arrangements of sub-100 nm building blocks. As such, fabricating these materials using conventional lithographic methods is extremely costly. On the other hand, bottom-up assembly of nanoparticles into crystalline superlattices offers opportunities to explore the scalable fabrication of 2-...
In my dissertation, Knowing How to Feel: mapping affective epistemologies of ignorance through numbness, I examine the ways by which numbness contributes to harmful “epistemic resilience,” or the phenomenon whereby systems of meaning remain stable despite counter evidence or attempts to alter them (Dotson 2014). I am most importantly concerned...
Protein homeostasis, or proteostasis, is essential for preserving all cellular functions and involves a balance of protein synthesis, folding, trafficking, and degradation. A collapse in proteostasis is a common feature of many neurodegenerative disorders that are characterized by the accumulation of insoluble protein aggregates in the brain. Parkinson’s disease (PD)...
This dissertation examines the interactional mechanisms that undergird exercises of regulatory authority in expert work settings. In the first chapter, I argue that, in the aftermath of a crisis (in this case, induced by a major regulatory event), organizational actors face environments of high uncertainty which challenge rational models of...
In recent years, the social sciences have been ensnared in a crisis in which many research findings cannot be replicated (Ioannidis, 2005; Open Science Collaboration, 2015; Camerer et al., 2016; Makel & Plucker, 2014). This crisis has been attributed to a variety of problems including lack of transparency about research...
This dissertation addresses two distinct but related questions. First, how should we conceive of social freedom? Second, given this conception, what ideals would best satisfy the demands we are under as citizens and moral agents? In answer to the first question, I defend a novel account of social freedom, where...
Regulatory T (Treg) cells are required to control immune responses and maintain homeostasis, but are a significant barrier to antitumor immunity. Conversely, Treg instability, characterized by loss of the master transcription factor Foxp3 and acquisition of proinflammatory properties, can promote autoimmunity and/or facilitate more effective tumor immunity. A comprehensive understanding...
Existing nonlinear optimization methods have proven reliable over the past few decades for a wide range of applications but have critically relied on accurate function and gradient evaluations. Modern nonlinear optimization problems arising from machine learning and scientific computing applications are increasingly complex and large scale, which make accurate evaluations...
This dissertation reorients political theory to the concepts of use and utility for a more critical and emancipatory perspective on contemporary communal life. The reorientation entails a recovery of Aristotle’s and Marx’s overlapping approaches to use, whose contemporary reception indexes the surprising alignment of critical political theory with economics. That...
Semiconductor nanocrystals possess unique photophysical properties that make them desirable for many optoelectronic applications such as photovoltaics, LEDs, and quantum computing. When the size of a semiconductor is reduced to below the excitonic Bohr radius of the material, its carriers becomes quantum confined resulting in drastic changes to optical, electronic,...
Nanomaterials offer unique properties not seen in their macroscopic kin. They can be used in printed electronics, as catalysts, and so much more. However, their diminutive size complicates materials processing techniques. They can easily aggregate become no longer useful. A solution to this is to use a polymeric surfactant such...
The field of robot design mostly focuses on careful construction of complex control and planning algorithms (e.g., tuning neural network weights) which bear sole responsibility for improving task performance, while the robot’s body is often assumed to be part of the environment. In nature, however, biological organisms co-evolve both their...
One of the most pressing open questions in star formation is the role of magnetic fields relative to turbulence and gravity, and how these three processes set the stellar initial mass function and star formation efficiency. In this work, we present the state of BLAST-TNG (the Balloon-borne Large Aperture Submillimeter...
Critical pedagogies offer a particular orientation towards education that understands the process of learning as inherently political. These frameworks demand explicit political attention by teachers to support student development of practices needed to create a liberatory world. Recent work evidences the positive impact critical pedagogies have on students academically, civically,...
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease, affecting children and adults. Chemotherapy regimens show high response rates but have debilitating effects and carry risk of relapse. Until now, no targeted therapy has been approved. In addition, 40% of patients will relapse and their treatment options are limited because...
Language models are the foundation of many natural language tasks such as machine translation, speech recognition, and dialogue systems. Modeling the probability distributions of text accurately helps capture the structures of language and extract valuable information contained in various corpora. In recent years, many advanced models have achieved state-of-the-art performance...
The logistics of policy implementation can lead to a delay from when the actual change in behavior occurs, leading to a shift in a time series. Using change point analysis allows for the data to determine where a change in mean, or other parameters, occurred. But when policy is implemented...
We live in an increasingly computational world; one that, in the near term, may require everyone to be computationally literate. Computer science (CS) education has greatly increased its reach in the last two decades with an increasing number of students having access to formal computer science classroom experiences in the...
Materials science has been central to human advancement since time immemorial. There has always been curiosity around studying the processes required to extract materials, examine their structure, and ultimately tailor their properties to meet human needs. Over the last few centuries, the ability to tailor material properties was driven by...
To be tempted is to be conflicted, but the conflict is not one of oscillation between two good options. Rather, it is normally easy to act on temptation and difficult to act against it. But this is puzzling, because unless temptation is a force that acts on us, it’s not...
Object Detection is a core computer vision problem and can facilitate many image understanding problems. Object Detection has witnessed significant progress in the past decade especially after deep learning is successfully applied to this field. Most of the detection models focus on generalizing the trained model to unseen samples of...
Engineering heat transport in materials is essential for thermal management in a wide range of technologies, from batteries to thermoelectrics. Materials host a wide spectrum of heat-carrying phonons, which vary in their frequency, spatial extent, and degree of plane-wave character. This diversity in phonon properties leads to complex behavior, especially...
In this dissertation, we aim to develop efficient algorithms with theoretical guarantees for several data-driven decision making problems. Specifically, we study the data-driven deci- sion making from three different perspectives: statistical learning, nonconvex optimization, and control of stochastic system. This dissertation contains three parts. In the first part, we study...
Nanocarriers as structures with at least one dimension in the nanometer scale are capable of loading small molecule therapeutics that would otherwise have poor bioavailability, non- specific uptake, and off target effects. Polymeric nanocarriers can be modified to tune their chemical and biological behavior to better suit the intended application....
The dissertation builds on my current research to demonstrate the connection between affect and learning through machine learning and qualitative analysis of interactions where players use a complex systems game. The project is threefold: First, I developed a thinking and learning intervention, the agent-based modeling simulation Ant Adaptation. I showed...
With growing system complexity and closer cyber-physical interaction, there are stronger needs for cyber-physical systems to adapt to the dynamic environment and improve their runtime performance. However, especially for safety-critical systems, the ability of such adaptation and improvement is often restricted by multiple factors, such as limited resources, stringent timing...
In the seventeenth and eighteenth centuries, hundreds of Venetian women began musical training in childhood to become professional musicians, known as figlie di coro (daughters of the choir), in the four charitable Ospedali Maggiori. These women overcame childhood poverty and abandonment to awe prestigious guests with their skills and even...
This thesis consists of three chapters: two are empirical studies of policy design in small-business lending markets, while the final is a large-scale retrospective of retail mergers. Chapter 1 examines moral hazard in loan guarantee programs. To address credit constraints in small-business lending markets, policymakers frequently rely on loan guarantees,...
Cancer is a top leading cause of deaths worldwide, among which pancreatic cancer and liver cancer are top leading cause of cancer-related deaths. Despite recent developments in cancer treatment, pancreatic and liver cancers still have a high mortality and low life expectancy, especially when diagnosed at advanced stages. Earlier cancer...
This dissertation studies three aspects of healthcare market regulation.
Chapter 1 studies the optimal design of quality scores for health insurance plans. Regulators often generate quality scores to help consumers with limited information about product quality, as in schooling, healthcare, and financial markets. When designing scores, regulators must not only...
With the ever-increasing demand for more complex functionalities and miniaturization of photonic devices, the design of such devices requires a whole new different approach, deviating from classical photonic design approaches. Conventionally, the design of a typical photonic device starts with a prior knowledge, intuition, and practical experience of specific behavior...
This paper studies the joint importance of dissemination and the structure of firms’ information networks in the pricing of value relevant financial information. I first document that disruptions to the dissemination of information on Twitter.com cause the market to react less to earnings news. Using ten staggered Twitter outages, which...
In the adult hippocampus of many mammalian species, populations of newborn dentate granule cells (DGCs) are continuously generated and undergo subsequent activity-dependent neuronal maturation and incorporation into the preexisting hippocampal circuitry. Increasing evidence has demonstrated that these young adult-born DGCs (abDGCs) participate in numerous cognitive and affective processes such as...
My research at northwestern with Dr. Christina Zelano focused on the human amygdala subnucleithat receive monosynaptic input from the olfactory bulb. Surprisingly little is known
about these brain regions, including their potential roles in olfactory and nonolfactory
processing. During my PhD, I completed three projects aimed at furthering our understanding...
This dissertation develops a causal theory of the relevant alternatives in a situation and applies this theory to the semantics and epistemology of conditionals, the theory of knowledge, and the epistemology of stereotyping. The first chapter presents the theory of causal models and causal alternatives. The second chapter applies this...
Missing data are often described as an annoyance in research and generally presented as a source of error or bias during analysis. To this end, methods that center on planned missingness are an underappreciated and powerful tool that can actually be used to improve data collection and the validity of...
For stochastic simulation optimization in a modern computing era, we introduce a new parallel framework for solving very large-scale problems using a ranking & selection (R&S) approach that simulates all systems or feasible solutions to provide a global statistical guarantee. We propose a parallel adaptive survivor selection (PASS) framework that...
Myoelectric pattern recognition-based upper limb prostheses measure electromyographic (EMG) signals from the residual limb and learn to identify muscle activity patterns that correspond to intended gestures. To train an accurate pattern recognition controller, it is essential that the training signals typify signals measured in real-world scenarios. When these conditions are...
Individual responses are an important determinant of public policy effectiveness. Development policies often try to remove barriers that limit the ability to make the preferred choices, hoping that this will lead to prosperity at the individual and aggregate levels. However, removing some, but not all, barriers can lead to undesirable...
This dissertation centers gay and lesbian activists, their lawyers, and public interest litigation organizations in a genealogical understanding of the evolution of human rights law in the LGBTIQ+ issue space. I ask why sexual minorities turned to the courts in pursuit of the decriminalization of homosexual sex. Empirically, I examine...
Ensuring adequate water quality is essential for human health and for effective allocation of resources in agriculture, energy, and manufacturing. However, the current state-of-the-art for water quality testing requires expensive equipment and technical expertise to analyze samples and takes days to obtain results from off-site labs, making it inaccessible to...
Wearable-based human activity recognition is well-studied in the machine learning and pervasive computing community. A large corpus of studies focused on using wearable sensors to recognize health-related behaviors that involve high periodicity in the sensed signal, such as sitting, walking, and running. Other activities that occur less frequently throughout the...
SAMDI-MS, which stands for self-assembled monolayers (SAMs) for matrix-assisted laser desorption ionization (MALDI) mass spectrometry (MS), is a powerful tool that has enabled the development of novel high-throughput screening and experimentation methods for decades. SAMDI-MS works by immobilizing analytes to functionalized SAMs prior to MS analysis and is capable of...
Reproduction requires a complex orchestration of processes from the formation of the reproductive system through the successful development of the fetus, and nutrients are necessary to fuel these processes during many aspects of reproduction. Zinc is an essential metal that is fundamental in gamete maturation, gonadogenesis, and fertilization. Disruption in...
No two cells in a population are identical to each other. Cell populations are almost universally heterogeneous, with their heterogeneity or variability often underlying complex emergent behavior and phenotypes. Heterogeneity presents a challenge to the discovery, characterization, and control of multicellular systems. Heterogeneity exists across multiple scales, ranging from the...
The first chapter of the dissertation analyzes a moral hazard problem where a firm incentivizes a team of complementary workers in the presence of trust concerns. As we show, when concerned about team members not trusting each other, the firm typically sacrifices statistically-relevant information, compensating some workers based solely on...
In most markets, consumers of goods and services have vastly more options available to them than they will consider closely. At the point of making a decision, consumers are choosing between only a small subset (i.e., a consideration set) of all possible alternatives. The preceding process that forms these consideration...
Over 10 billion tons of concrete are produced for the construction industry every year, making concrete the second most used substance on Earth, only surpassed by water. With such high importance as a building material, there is significant need for the ability to accurately model concrete behavior. As a quasi-brittle...
Anxiety and depression are highly prevalent, recurrent, and major public health problems. Decades of research has uncovered associations between symptom dimensions of anxiety and depression and abnormal neural activation across executive control-, threat-, and reward-related networks. Recent studies have developed a hierarchical symptom structure of anxiety and depression termed the...
The development of functional materials with rationally designed hierarchical structure is an interdisciplinary challenge. Looking to nature for inspiration, we use small molecules that
engage in directed self-assembly through carefully tuned intermolecular interactions to construct
materials that have structure at multiple length scales. In this work, supramolecular structures
formed using...
From energy to materials, hydrocarbon chemistry drives our world. Stemming from the petrochemical industry, our understanding of CxHy combinations has allowed society to flourish, and hydrocarbons will likely remain valuable species in our future even as we transition to greener carbon and hydrogen sources. Currently, one of the most efficient...
Engineering responses of soft materials at hierarchical time and length scales is of great interest to both fundamental science and technological applications. In recent years, the hybridization between emerging soft condense matters and conventional hard condense matters keeps enriching the materials library of humankind and opens another largely-uncharted venue for...
Bioelectronic devices at the biotic/abiotic interface face a number of key challenges that include device degradation when exposed to biological fluid, their elicited immune response due to mechanical mismatch, and poor signal transduction. Organic electronic materials and their devices, such as organic electrochemical transistors (OECTs) address these shortcomings. They can...
Predicting pediatric spinal deformity (PSD) from X-ray images collected on the patient's initial visit is a challenging task. This research provides a bio-informed framework based on a mechanistic machine learning technique with dynamic patient-specific (PS) parameters to predict PSD. We provide a geometry-based bone growth model that can be utilized...
“(Being a) Feminist (is a) Struggle: Intersectional Feminist Politics in the Era of the Women’s March” argues that contemporary feminist politics are characterized by debates and contestations concerning the political demands of intersectionality. Contemporary feminist theory and politics are particularly and peculiarly preoccupied with making these judgements about the political...
Methanotrophs, bacteria that can metabolize methane, remain a promising solution to mitigating the effects of climate change by removing atmospheric methane and converting it to useful chemical precursors. However, a full understanding of the main enzyme they use to oxidize methane, particulate methane monooxygenase (pMMO), is critical for harnessing their...
This dissertation contains two chapters. The first one is on microenterprises in developing countries and how they face competition from large corporations. The second one is on estimating the causal effect of childcare availability on the formation and persistence of gender gaps in the Mexican labor market. The first chapter...
This dissertation explores the relationship between cultural production in Puerto Rico from 2005 to the present and the unfolding debt crisis on the island. I explore the relationship between colonialism as an institution, coloniality as a broader structuring of power, and the current debt crisis by examining cultural objects that...