Integrated circuits have been continuously scaled to increase speed and integration density as a means to improve the performance or pack more functionality. However, an extremely enormous amount of effort is needed to further scale the dimensions in deep submicron technologies. As technology scaling is slowing down and design complexity...
"How did the Civil Rights Movement bring about change?" In answer to that question, this dissertation argues that the splintering of purity rhetoric within the intimate environments of home and sanctuary both inhibited and empowered white and African-American religious practitioners to seek social change. To make this argument, this project...
The work of this dissertation was aimed at synthesizing new types of nanoparticle-DNA conjugates, investigating their chemical and physical properties, and exploring their biodiagnostic applications. Chapters Two and Three describe the synthesis of new types of nanoparticle-DNA conjugates: (1) silver nanoparticle-DNA conjugates (DNA-Ag NPs) and (2) 2-nm gold nanoparticle-DNA conjugates...
As manufacturing technology moves toward fundamental limits of silicon CMOS processing, it is increasingly important to utilize the full potential of available transistors and interconnects. While manufacturing technology faces fundamental limits inherent in physical laws or material properties, design and verification technology faces fundamental limitations inherent in the computational intractability...
In several neurodegenerative diseases, the microtubule-associated protein tau self-aggregates to form filaments that accumulate in neurons and/or glia, although the relationship between tau aggregation and cell death is a subject of debate. The amino terminus of tau is involved in conformational changes that appear critical for filament formation, hinting at...
Inactivation of tumor suppressors genes, which encode regulatory proteins critical for maintaining normal cellular function, is a common occurrence in cancer. Ikaros is a hematopoietic-specific zinc finger protein that functions as a differentiation regulator and has properties of a tumor suppressor. Ikaros functions to regulate gene expression as a component...
The set of experiments described here test the hypothesis that the declarative memory system supported by the medial temporal lobe and habit/procedural memory supported by the basal ganglia are recruited when learning novel category representations. The theory guiding specific hypotheses about these neural systems and their operation in category learning...
Organic light emitting diodes (OLEDs) are fabricated and characterized on anodes modified by a variety of surface treatments. OLED performance response is correlated to the treatment conditions with current-voltage (I-V) measurements and impedance spectroscopy. Small-scale OLED arrays are fabricated using a novel shadow mask approach and are characterized with electrical...
The electronic properties of various transparent conducting oxide (TCO) surfaces are probed electrochemically via self-assembled monolayers (SAMs). A novel graftable probe molecule having a tethered trichlorosilyl group and a redox-active ferrocenyl functionality (Fc(CH2)4SiCl3) is synthesized for this purpose. On as-received ITO, saturation coverage by a close-packed monolayer having of 6.6...
Despite its prevalence, cost, and association with high risk for negative outcomes, there is a lack of empirically-based procedures for effective treatment of dual diagnosis in adolescents. The present study attempts to address the need for research informing effective treatment of this population. Strengths have been found to predict positive...
This dissertation examines the role of market makers in making markets for options and futures on Chicago's derivatives exchanges. Recent institutional and technological changes in the ways that financial products are traded have given rise to the possibility of markets without market makers, raising the question of how these developments...
The primary purpose of this study was to describe what comprises an undergraduate compositional identity. Building upon recent research investigating musical identities with a social psychological framework (Macdonald, Hargreaves, & Miell, 2002), I examined the confluence of socially based experiences that shaped four undergraduate composers' lives. Specifically, this study investigated...
Lead poisoning is the most common environmentally-caused disease in the United States and is threat to human health worldwide. Although efforts to prevent lead exposure have increased throughout the years, lead poisoning still remains a common problem. Lead toxicity is more prevalent in children, who suffer from permanent neurodevelopment and...
Herpesviruses require axonal transport for the successful establishment of infection in peripheral ganglia (retrograde transport), and the subsequent spread to exposed body surfaces following reactivation from latency (anterograde transport). Viral progeny are assembled and spread to other tissues or hosts during egress. I focused on viral proteins which modulate directed...
Magnetic resonance imaging (MRI) is a technique widely used in both clinical and experimental settings to produce high-resolution images of opaque living organisms without utilizing ionizing radiation. Currently, MR imaging is augmented by contrast agents; however, these small molecule Gd(III) chelates are confined to extracellular and vascular regions of the...
Let X be a quasi-projective complex variety. It follows from the work of Voevodsky that the motivic cohomology of X, denoted as $H^{p,q}(X)$ where q and p are integers with q nonnegative, can be represented in the triangulated category of motives over the field of complex numbers, denoted as $DM^{eff,-}_{Nis}$....
Separation of DNA molecules by electrophoresis through entangled polymer solutions continues to be an important tool for genetic analysis, especially Sanger-based DNA sequencing. Separations of DNA on microfluidic devices are much more efficient than in capillary electrophoresis (CE) systems, such that the implementation of DNA sequencing onto microchips promises to...
This dissertation comprises three chapters, each focusing on a different question in economic theory. The first two chapters focus on repeated games and reputations, while the third is about large games. In "Cooperation and Community Responsibility", I study whether cooperation can be sustained between communities where members interact repeatedly but...
The small heat shock protein αB-crystallin is expressed primarily in lens and muscle tissue, but it is also found in lung, kidney and many cancers. Regulators of αB-crystallin have been identified almost exclusively using mouse muscle and lens specific models. It has been well documented that αB-crystallin is expressed in...
The first chapter of this dissertation studies a continuous-time agency model where the agent controls the drift of the geometric Brownian motion firm size. The changing firm size generates partial incentives, analogous to awarding the agent equity shares according to her continuation payoff. When the agent is as patient as...
One of the most commonly used techniques for classification problem is logistic regression. For example, logistic regression for a binary response assumes that the odds Pr(y = 1|x)/Pr(y = 0) = exp(a+bx). However, in reality, the pattern of the data can be so complicated that logistic regression model often fails,...
N-Heterocyclic carbene catalysis has recently emerged as an important field in organic chemistry. Two new strategies have been developed to advance the use of N-heterocyclic carbenes (NHCs) as Lewis-base organic catalysts. The first approach utilizes NHCs to catalyze the generation of homoenolates and the conjugated Breslow intermediate is added to...
Time-resolved in situ synchrotron x-ray scattering studies of particle orientation in polymer-clay nanocomposites under simple shear and complex flow were performed. Shear flow experiments used an annular cone and plate x-ray shear cell to allow measurement of platelet orientation within the flow-gradient plane.
Intercalated nanocomposites were made by dispersing organically...
Epstein Barr Virus (EBV) is associated with malignancies of lymphoid and epithelial origin. While the precise role of EBV in oncogenesis remains elusive, latent membrane protein 2A (LMP2A) is detected in all EBV-associated malignancies, implicating LMP2A in their pathogenesis. Interestingly, LMP2A is expressed in EBV-associated malignancies such as Burkitt's Lymphoma,...
Chapter one investigates the impact of agents' expectations about future fundamental economic disturbances (news) on macroeconomic dynamics. Several intuitive tests provide insight into the information content of the yield curve and its' ability to identify these 'news' disturbances. Bayesian estimation of a dynamic stochastic general equilibrium (DSGE) model using conventional...
Tonia René Holverson The HPV genome contains a bipartite promoter system that regulates the expression of early and late gene transcripts. The early proteins include the replication proteins E1 and E2, the oncoproteins E6 and E7, and the late functioning proteins E4 and E5. The late proteins include the capsid...
Estrogens are traditionally thought to act through a nuclear receptor-mediated mechanism to regulate gene transcription in target tissues. The hippocampus has been shown to be sensitive to estrogen; estrogen regulates GABAergic inhibition and spine density of dorsal CA1 pyramidal cells. However, very few neurons expressing nuclear estrogen receptors (ERs) have...
The kinetoplastid protozoan <em>Trypanosoma brucei</em> is the causative agent of African trypanosomiasis, affecting humans, and Nagana disease, affecting cattle, prevalent in regions of sub-Saharan Africa. Our lab demonstrated that the flagellum of <em>T. brucei</em> is enriched in lipid rafts, membrane areas composed of sphingolipids, sterols, and proteins that serve as...
This dissertation explores the factors that influence the creation and interpretation of novel denominal verbs in English. Of particular focus is the potential influence of one factor, termed here the Semantic Category Distribution Effect. The Semantic Category Distribution Effect involves the type frequency distribution of existing forms of a given...
The last two decades in nineteenth-century West Africa witnessed a two-fold movement, namely the territorial expansion of French colonial empire and the first attempts to extend biomedicine through mass vaccination to control smallpox epidemics. This study provides both a deep history and conceptual framework to analyze the relationship between the...
This study examined the effects of swallow task on swallow physiology, respiratory phase relationships, and oxygen saturation in healthy adult males. This study hoped to provide a building block to clinically relevant research with individuals with compromised swallowing and respiration. Subjects included 40 healthy adult males with no history of...
High-performance scientific computing in a modern age uses parallel techniques at a scale of hundreds of thousands of processors. These large-scale applications have I/O system workloads that are primarily driven by small, sparse I/O operations. While parallel file systems have provided application developers with scalable peak I/O bandwidth for large,...
This dissertation explores a seventy-year period of community growth and activism among African Americans in nineteenth-century Iowa, showing how citizenship was defined, contested, expanded and confined. Antebellum black migrants lived on the margins of a hostile society and struggled for equal citizenship using their labor, their community institutions, the legal...
The three empirical analyses in this dissertation study the effects of workers' compensation benefits on individual behavior and household consumption as well as the impacts of workplace injuries and illnesses on economic outcomes for affected workers.
In Chapter 2, I study incentive effects of state workers' compensation programs, exploiting substantial...
Leakage currents limit the operation of high performance type II InAs/GaSb superlattice photodiode technology. Surface leakage current becomes a dominant, limiting factor to the ideal performance of a photodiode, especially at the scale of a focal plane array pixel (< 25 µm), and must be addressed. A reduction of the...
During movement, the dendrites of spinal motoneurons receive steady excitatory and inhibitory synaptic input from supraspinal sources, interneurons, and sensory afferents. Motoneurons also have dendritic voltage sensitive ion channels. Most notable is a persistent inward current (PIC), which can enhance the amplitude of synaptic input by several fold. PICs are...
Filopodia play a central role in proper cell navigation; they extend from the cell surface and scan the local environment to guide the cell to its proper destination. These dynamic events require precise mechanisms for the turnover of key molecules which determine the morphology of filopodia. As of yet, such...
Chapter 1 describes the homopolymerization of styrene and the copolymerization of ethylene and styrenic comonomers mediated by the single-site bimetallic "constrained geometry catalysts" (CGCs), (µ-CH2CH2-3,3'){(η5-indenyl)[1-Me2Si(tBuN)](TiMe2)}2 [EBICGC(TiMe2)2; Ti2], (µ-CH2CH2-3,3'){(η5-indenyl)[1-Me2Si(tBuN)](ZrMe2)}2 [EBICGC(ZrMe2)2; Zr2], (µ-CH2-3,3'){(η5-indenyl)[1-Me2Si(tBuN)](TiMe2)}2 [MBICGC(TiMe2)2; C1-Ti2], and (µ-CH2-3,3'){(η5-indenyl)[1-Me2Si(tBuN)](ZrMe2)}2 [MBICGC(ZrMe2)2; C1-Zr2], in combination with the borate activator/cocatalyst Ph3C+B(C6F5)4- (B1). Under identical styrene homopolymerization conditions,...
Influenza virus assembly and budding is a complex process involving the organization of viral membrane proteins on the cell surface, incorporation of the segmented RNA genome, and formation of viral particles that must bud from the cell by pinching off from the plasma membrane. Interactions between the soluble influenza virus...
Metal nanoparticles in polymeric matrices are of particular scientific interest due to their useful ability to self-assemble into complex nanocomposites. Recent examples involve using ultrathin diblock copolymers coupled with metal nanoparticles in the fabrication of novel electronic, magnetic and photonic devices. As this ordering process takes place far from equilibrium...
Short-range stiffness (SRS) of a skeletal muscle describes the muscle's capability to resist external perturbations before the nervous system can intervene. Knowledge of the SRS of individual muscles is critical in understanding their contributions to single joint stiffness and whole limb stability. While the dependence of SRS on muscle force...
Two main topics are addressed in this dissertation: (1) adhesion in hydrogels; (2) interfacial interactions between model glassy polymers. A self-assembly technique for the formation of hydrogels from acrylic triblock copolymer solutions was developed, based on vapor phase solvent exchange. Structure formation in the gels was characterized by small angle...
In urban areas, an accurate evaluation of ground deformations from various construction activities requires one to properly consider both the probable ground strain level under expected working conditions and the recent stress history of the soil. For well-designed projects, the levels of ground strains typically are less than 0.5%, emphasizing...
Upward influence is an important vehicle for employee participation in work and decision-making. Research suggests that the forms and success of upward influence vary according to agent attributes, the supervisor-employee relationship, and the work context (Waldron, 1999; Wilson, 2002). Unexamined within this array are employee attempts at shaping their own...
Multi-hop wireless networks hold promise for increasing network capacity, lowering power requirements, and improving coverage over traditional cellular networks. However, their widespread adoption is hampered by challenges that include: 1) unreliable and complex routing protocols due to the transient nature of wireless nodes, 2) difficulties in guaranteeing quality of service...
Metal nanoprisms are a novel class of anisotropic nanomaterials with unique optical properties dependent on their size, shape, and composition. Silver nanoprisms are of particular interest because their surface plasmon resonance bands are readily tunable in the visible and near-IR region. The objectives of this thesis research focus on photochemical...
A novel cryogenic variable temperature UHV STM has been constructed and utilized to investigate the dynamical behavior of isolated organic molecules covalently bound to silicon surfaces.
The microscope can be operated from 8-300 K, and exhibits extremely low drift rates. A new design has been implemented for the rails (used...
This dissertation demonstrates how self-assembly can direct nanoscale ordering and optimize electronic properties of organic semiconductors, as well as organic-inorganic hybrids. In excitonic solar cells, controlling the ordering and interfaces between electron-transporting (n-type) and hole-transporting (p-type) domains is crucial. In addressing this challenge, hybrid nanostructures were designed by mineralization of...
This dissertation, "Myth and the Modern Problem: Mythic Thinking in Twentieth-Century Britain," argues that a widespread phenomenon best described as "mythic thinking" emerged in the early twentieth century as way for a variety of thinkers and key cultural groups to frame and articulate their anxieties about, and their responses to,...
IL-6 is a pleiotropic cytokine involved in both immune and non-immune functions. In the immune system, IL-6 induces terminal differentiation of B cells into plasma cells, thereby promoting antibody production. IL-6 stimulates growth of T cells by enhancing the expression of the IL-2 receptor, and IL-6 also causes differentiation of...
Granular matter and living cells represent two extremes of what have come to be regarded as complex systems - systems characterized by a richness in global behavior that is not easily deduced from the interactions of their individual parts, even when those interactions are simple and well understood. On the...
Actin polymerization is responsible for the protrusion of filopodia and lamellipodia in immune, cancer, and other motile cells, as well as for propulsion of some intra cellular pathogens. Protrusion of a lamellipodium by the very filaments supporting the membrane load operates by the Brownian ratchet mechanism, with overall organization governed...
A primary limitation of non-viral gene therapy is the low level of expression achieved. One of the reasons that higher expression is not achieved is that there are many physical obstacles that prevent the DNA from reaching the nucleus to be expressed. A plasmid must cross the cell membrane, traverse...
On average, homosexual people are more gender nonconforming than heterosexual people. They also show increased distress, possibly due to their stigmatized minority status. Not surprisingly, gender nonconformity and psychological distress may be related, particularly in homosexual men (e.g., Skidmore, Linsenmeier, & Bailey, 2006), although the mechanisms explaining this relationship have...
A study of the optical properties and superconductivity in semiconductors is presented using the highly precise all-electron full-potential linearized augmented plane wave (FLAPW) density functional calculations.
Optical properties [$\varepsilon(\omega)$,$n(\omega)$,$k(\omega)$,$R(\omega)$ and $\alpha(\omega)$] of some III-V semiconductors [InAs, InSb, GaSb, and AlSb] and their critical point (CP) energies, are calculated from the...
In the same way that a sculptor shapes a block of stone to reveal the ideal form within, one's relationship partner can help one to become more like one's ideal self (Drigotas, Rusbult, Wieselquist, & Whitton, 1999). This interpersonal process is called "the Michelangelo phenomenon." The current research examines whether...
The perinucleolar compartment is a nuclear substructure that is associated with, but structurally distinct from the nucleolus. Previous studies have shown that the PNC preferentially forms in cancer cells and PNC prevalence (% of non-mitotic and non-apoptotic cells in a population with one or more PNC) is a prognostic in...
We can represent many real-world data sets as data streams and/or high-dimensional data. Major stock market such as New York Stock Exchange (NYSE) trades more than 8000 financial products daily, which generates massive trading time series in the form of data streams. NetFlow and DNS querying data generated by real-time...
In three essays, this dissertation examined the associations between child characteristics, interparental discord and various aspects of child development and physiological functioning. In the first essay, using longitudinal, nationally representative data on infants and their families from the early childhood longitudinal study (ECLS-B), results revealed small, but significant associations between...
This dissertation aims at contributing to the literature of organizational learning and organizational change. More specifically, this dissertation focuses on three fundamental issues of exploitation and exploration: the relationship between exploitation and exploration, the balance of exploitation and exploration, and the performance implications of exploitation and exploration. This dissertation comprises...
Cellular interactions are important for the development and maintenance of tissue structural integrity. In the developing neuroepithelium, the adherens junction proteins, N-cadherin and β-catenin, are highly enriched at the apical surface of the proliferative ventricular zone and have been suggested to have critical functions in ensuring the proper development of...
This dissertation is a textual history of Thomas Paine's Common Sense and the American independence movement during the first half of 1776. The study uses the methodologies and vocabularies of rhetorical studies, early modern history, and political theory to analyze the 180-degree turn in colonial public opinion away from a...
Humans routinely answer questions, make decisions, and provide explanations in the face of incomplete knowledge and time constraints. From everyday questions like "What will it cost to take that vacation?" to policy questions like "How can a carbon taxing scheme affect climate change?" we often do not have all the...
Drawing on seven years of ethnographic fieldwork, as well as interviews, crime statistics, and census data, this study documents the demolition and redevelopment of a predominately African-American housing development in Chicago. I describe how living in a hypersegregated, high crime neighborhood affects the way residents use, affectively feel, and navigate...
The prediction of multicomponent adsorption equilibria from pure component data alone has been an active research area for over forty years. The Ideal Adsorbed Solution theory (IAS) has been the standard method of doing so, but contains an embedded assumption of Langmuir mixing. This assumption causes its predictions to be...
In the first chapter of my dissertation, I study the effects of an exogenous increase in government spending in models incorporating price and wage nominal rigidities. I find that the effects of price stickiness on the output multiplier depend crucially on the behavior of the monetary authority. If the monetary...
The recent tightening of permissible NOx release from diesel-powered engines has intensified the search for a catalytic system that can effectively remove NOx under challenging diesel exhaust conditions. Hydrogen-assisted selective catalytic reduction (H2-SCR) using supported palladium catalysts offers significant promise for lean NOx treatment due to its high activity at...
Conjugated organic molecules and polymers hold significant promise for use as active materials in electronic devices. Employing such "soft" materials can decrease cost of device fabrication, while enabling unique properties such as mechanical flexibility, large-area coverage, and highly tunable materials properties. A primary roadblock to the realization of this dream...
The kinetics of nanoscale Cu-rich precipitates of multicomponent concentrated steels has been investigated utilizing primarily APT and supplemented with a synchrotron radiation experiment, first-principles calculations, Thermo-Calc study, and CTEM (at the longest aging time). Results on mechanical properties and microstructure at a greater length scale are also presented. The studied...
The neurotropic alphaherpesviruses infect and spread trans-synaptically within the vertebrate nervous system. Recurrent diseases are often manifested at the periphery of the host organism but occasional dissemination of the virus to the brain results in fatal encephalitis. Interactions between viral and host cellular proteins are integral to the success of...
This dissertation combines critical ethnography, critical performance and historical analysis to examine three Trinidadian dance companies - Malick Folk Performing Company, Shiv Shakti Dance Company, and Noble Douglas Dance Company Inc. - asking how each choreographs Trinidadian discourses of race/ethnicity, class and national belonging through its own uniquely crafted embodied...
The addition of nanoparticles into polymer materials has been observed to dramatically change the mechanical, thermal, electrical, and diffusion properties of the host polymers, promising a novel class of polymer matrix composite materials with superior properties and added functionalities that are ideal candidates in many applications, including aerospace, automobile, medical...
The work presented in this dissertation focuses on ceramic anode materials for solid oxide fuel cells (SOFCs). The primary goal was to characterize the anode and relate the electrochemical behavior to the microstructure. The anode that was most extensively studied in this work was a composite of Gd0.10Ce0.90O1.95 (GDC) and...
Two experimental methods have been developed to induce flexural waves in concrete piles for which a portion of the shaft is accessible, and the test results were compared to theoretical solutions of flexural guided wave propagation. The pile response is measured and the results are analyzed to compute the group...
The important application for the infrared photodetectors is mainly thermal imaging by focal plane arrays (FPAs) for military and commercial purposes. So far, most mid-wavelength infrared (MWIR) and long-wavelength infrared (LWIR) FPAs are based either on HgCdTe (MCT) or quantum well infrared photodetectors (QWIPs). Even though those technologies are well...
Chemical vapor deposition (CVD) is a well-developed technique for growing thin films of a wide variety of materials, which relies on the development of new and better performing metal-organic precursors. To this end, three studies have been conducted into the compatibility of sulfur and phosphine containing ligands with low- and...
This thesis summarizes our research efforts on the application of the nano-structured anodic aluminum oxide (AAO) membrane in heterogeneous catalysis. Procedures for growing the AAO membrane in the center of an aluminum disc have been developed by appropriately masking the disk's perimeter during the anodization and etching steps. The remaining...
Metallic nanostructures are able to confine and manipulate electromagnetic fields because light can couple to free electron oscillations called surface plasmons (SPs). These plasmons exist on metal surfaces as localized (short-range) or as propagating (long-range) modes depending upon the size and geometry of the nanostructure. This dichotomy is primarily an...
This thesis investigates singlet exciton fission, a physical process that converts one singlet exciton to a pair of triplet excitons. Singlet fission was discovered nearly forty years ago, but the mechanism for this process is still not well understood. Recent work has suggested that singlet fission may be capable of...
In this research, the optical and electrical properties of graphene-based materials are investigated. In particular, "graphene oxide", which is an individual layer of graphite oxide, and its chemically reduced form, is probed in terms of its properties, and the properties of graphene oxide and chemically modified graphene oxide are compared...
This thesis attempts a combined theoretical/experimental investigation of two fundamental scaling laws in charge transfer reactions: how the rate of those reactions varies as a function of distance between an electron donor and an electron acceptor and how the rate varies as a function of the number of distinct pathways...
The Satake category is the category of perverse sheaves on the affine Grassmannian of a complex reductive group G. The global cohomology functor induces a tensor equivalence between the Satake category and the category of finite-dimensional representations of the split form of the Langlands dual group of G. We give...
The task of designing porous materials for use in specific applications requires a detailed understanding of the adsorption process and how adsorption is affected by material properties. Applications of interest include maximizing gravimetric or volumetric adsorption capacity for hydrogen and carbon dioxide and increasing the selectivity for carbon dioxide in...
Two subjects are the focus of this dissertation: Au/TiO2 catalyst used for oxidation of CO at low temperature and siloxane nanocages, a novel material (~2nm) recently developed in our group
While bulk gold is chemically inert, gold supported as nanoparticles is remarkably active for the oxidation of carbon monoxide at...
An efficient unified incremental high-level and physical-level synthesis algorithm was presented in Chapter 2, which enable the tight integration between high-level and physical-level design. Chapter 3 presented a temperature-aware high-level synthesis algorithm built upon the framework of Chapter 2. Temperature variations and hot spots account for reliability issue and require...
In this thesis, I argue that life and soul as analyzed in De Anima are examples of what Aristotle calls a "pros hen legomena" structure, a structure in which various things are said to be living in relation to one thing, which is the central meaning of life. The various...
Since its emergence, the Ginzburg-Landau theory has had a tremendous success in describing thermodynamic properties of superconductivity. In the case of superfluid 3He, not all five fourth-order parameters in the theory are known. Only four combinations of the five parameters have been experimentally established and theoretical attempts to calculate the...
I/O performance has perpetually lagged well behind that of processors. This gap is made even more pronounced in the field of high-performance computing. While simply adding more network bandwidth and increasing the number of storage units is a simple way to increase theoretical peak I/O bandwidth, the software libraries for...
The work described in this dissertation focuses on the optical characterization of micron-sized structures with mesoscale (100-1000 nm) features to investigate of the optical analog to the quantum corral. Lithographically patterned arrays of metallic rings and ellipses were used to study how light can be manipulated and confined within these...
A striking aspect of human cognition is our capacity for acquiring and using complex knowledge structures, from learning the rules of algebra, to understanding the causal workings of a combustion engine or the structure and processes of the U.S. Congress. These structured representations underlie our ability to generate new inferences,...
The most important managerial criteria in supply chains are how to manage product, information and cash flows, and how to maximize profits by either increasing the revenue or decreasing the costs. Although the maximum benefits can be achieved if everyone follows the central planner's suggestions; unfortunately, the individual maximum profits...
With aggressive scaling down of feature sizes in VLSI fabrication, process variations, crosstalk and buffering have become critical issues to achieve timing closure in VLSI designs. Timing analysis and optimization techniques need to consider each of them and also their interactions. There are many statistical timing analysis researches to handle...
The contents of this dissertation are divided into two sections: (1) the preparation and characterization of quaternary rare-earth chalcogenides and oxychalcogenides and (2) the localized surface plasmon resonance (LSPR) spectroscopy of metallic nanoparticles fabricated by nanosphere lithography (NSL).
Single crystals of CsTmCoS3, CsYbCoS3, CsHoCoSe3, CsYbCoSe3, and CsYbZnSe3 have been prepared...
During interactions with our environment we must incorporate information about the mechanical properties of obstacles into our motor actions. Fundamental to these behaviors is the ability to simultaneously control movements of the hand while regulating the interaction forces that arise from contact with the environment. Although the neural control of...
Continuous fiber/epoxy composites have been widely used for structural applications due to their excellent mechanical properties, but the benefits of using these composites is limited by their lower than desired matrix-dominated properties. In this study, epoxy matrix in carbon fiber/epoxy composites was modified with graphite nanoplatelets to improve their mechanical...
Continental weathering and organic carbon (OC) burial in marine sediments are important processes because they act as sinks for atmospheric carbon dioxide. Continental weathering products provide information about provenance, marine sediment quality/quantity, denudation and continental crust composition. In this study I explore two topics that impact some of these issues...
MHC class II-restricted T cell responses are a common driving force of autoimmune disease. Numerous therapeutic strategies target CD4+ T cells hoping to attenuate autoimmune responses and restore self-tolerance. We have previously reported that i.v. treatment with antigen-pulsed, ethylenecarbodiimide (ECDI)-fixed splenocytes (Ag-SP) is an efficient protocol to induce Ag-specific tolerance...
This collection of essays on horizontal merger enforcement and dynamic contract breach addresses the question of what role, if any, should government play in enforcing the contracts of private parties? The government's appropriate role in these various settings depends, among other things, on the nature of the competition between private...
To navigate our environment we are often required to quickly and accurately derive simplified patterns from the complexity of life. This dissertation seeks to understand when the process of pattern perception occurs and when it goes awry and individuals falsely or inaccurately perceive patterns. I review the literature on various...
Humans determine the horizontal position of sound sources based on two cues: interaural time differences (ITDs) and interaural level differences (ILDs). Consistent with other evidence that these two cues are processed by separate neural mechanisms, Wright and Fitzgerald (2001) observed markedly different learning patterns in listeners who were trained on...