This dissertation considers how 21 trans and queer teenagers learned to create livable lives in unlivable worlds through routine participation on social media. Through a multi-year partnership with an interdisciplinary gender program in Chicago, I employed a humanizing qualitative design anchored by interview and participatory visual methods over three nested...
Molecules are highly social: they recognize one another and form bonds with those they are attracted to and repel those they are not. Some molecules establish strong bonds, while others form weak, transient associations. These interactions are ubiquitous in Nature and are integral to life. For at the basis of...
Nuclear receptors (NRs) are an important family of transcription factors that often regulate genes in response to ligands and by way of direct interactions with coactivator proteins. Many NR-coactivator pairs have been identified that cooperate to regulate transcription but fully understanding how NRs recruit specific coactivators involves learning which of...
Liquid helium-3 is a remarkable substance. Even prior to the discovery of superfluidity in 1972, liquid helium-3 was the paradigm of a strongly interacting Fermi liquid. At even lower temperatures, liquid helium-3 undergoes a phase transition to a p-wave Fermi superfluid. Over 40 years since its discovery, superfluid helium-3 is...
Crystalline and Framework materials make up a broad class of structures which are known for their precise and regular nature. Because these materials have predictable structures and compositions to their networks, they are widely used for several applications including electronics, optics, and catalysis. While these materials are of particular interest,...
Autonomous trucks (ATs) are envisioned to potentially revolutionize the logistics sector. The integration of autonomous trucks into the overall truck fleet will impact industry regulations and ease driver-related challenges. It also has the potential to improve road safety and reduce carrier costs. There is an extensive body of literature on...
This multi-study dissertation explores experiences of music education for students with disabilities with a particular focus on students with autism spectrum disorder (ASD). It is comprised of three distinct papers including two qualitative studies and a literature review. In the first study, I collaborated with Dr. Sarah J. Bartolome to...
Interfacial effects play a critical role in perturbing the properties of polymeric materials. The average properties of polymer materials with substantial specific interfacial area, e.g., ultrathin films, nanorods, and polymer nanocomposites, often deviate significantly from the bulk responses. Much of the past research has focused on systems in which free...
Volunteer-based physical crowdsourcing systems connect individuals to make unique contributions to solve local and communal problems and enable new services. A key challenge in enabling such systems is attracting enough willing volunteers who can make useful contributions to achieve desired system goals. While most volunteer-based systems provide volunteers flexibility to...
Many transcription factors (TFs) regulate oncogenic processes and are therefore desirable targets for drug intervention. However, few TF inhibitors have been developed to date due to a lack of specificity and few TF binding pockets. The Meade Lab has overcome these challenges by using cobalt-based complexes that disrupt Cys2His2 zinc...
A fundamental understanding of the photophysics involved in solar energy capture and conversion is crucial to the development of carbon-neutral energy technologies. Taking inspiration from nature, the photosynthetic reaction center (PSRC) is often modeled by simpler versions of its elements to allow for better control over the system and for...
Nanoparticles are nanometer scale (1-1000 nm) structures capable of encapsulating a diverse range of cargoes. Encapsulation of a cargo can drastically alter its pharmacokinetics, cytotoxicity, and biodistribution while allowing for informed and rational design of the nanoparticle itself. Poly(ethylene glycol)-block-poly(propylene sulfide) (PEG-b-PPS) is an amphiphilic diblock co-polymer able to self-assemble...
A replication crisis has enveloped several scientific fields since the early 2000s (see Baker, 2016). This has given rise to improved research and reporting practices (e.g., F. S. Collins & Tabak, 2014), as well as a cottage industry of research into issues of replication and reproducibility (e.g., R. A. Klein...
Soft materials are inherently fluxional, with morphologies and behaviors that are dictated by their solvation state. Thus, many organic systems cannot be reliably imaged by static dry state or cryogenic-transmission electron microscopy (TEM). This motivated us to pursue liquid cell (LC) TEM method development to study our own materials and...
This dissertation contains two studies. In Chapter 1 we investigate the relationshipbetween expansionary credit events and firms’ employment decisions. To overcome the
endogeneity coming from the supply side of credit we exploit the legal and political framework
in Mexico to examine the effects of local governments’ prepayment of loans, a...
My dissertation examines group dynamics of minority populations during times of violent conflict. By applying a comparative analysis to case studies drawn from the conflicts in Lebanon and Syria, I shed light on how and why minority groups decide to join a conflict, stay on the sidelines, go it alone,...
Graphene oxide (GO) is a heavily oxidized version of graphene, which is often made by oxidative chemical exfoliation from graphite powders. The reaction decorates the graphene sheets with oxygen-containing functional groups including hydroxyl and epoxide groups on the basal plane, as well as carboxyl groups on the edge, rendering the...
Structural colors originate from the interaction between the incident light and a surface with periodic submicron structures. They enable the creation of a spectrum of nonfading colors, potentially replacing toxic metal oxides and conjugated organic pigments. However, significant challenges remain, including lack of contrast needed for the complete gamut of...
Kidney transplantation remains the best and most cost-effective treatment for patients with end stage kidney disease, and the number of kidney transplants performed in the U.S. annually has increased steadily since 2015. To ensure transplant success, kidney transplant recipients (KTRs) are often prescribed lifelong, complex medication regimens that include immunosuppressants,...
We introduce empirical measures to study the $L^2$ norms of restrictions of quantum integrable eigenfunctions to the unique rotationally invariant geodesic $H$ on a convex surface of revolution. The weak* limit of these measures describes the dependence of their size on $H$ in terms of the angular momentum. The limit...
Algorithmically-driven social platforms present a challenge for self-presentation and identity management by obscuring audiences behind algorithmic mechanisms. Users are increasingly aware of this and actively adapting through folk theorization, but we do not know how users are coping with the constant change endemic to these platforms. We also do not...
This dissertation interrogates the quality of sincerity as it appears throughout John Locke’s work on religious toleration and Christian theology. Sincerity, and the framework it provides, offers a means to draw together his political and theological works, as well as to appreciate both his radical potentialities and conservative impulses. The...
In this thesis we study two problems, one in unsupervised learning - k-means clustering and the other in a supervised learning setting with the presence of adversarial perturbations. We do a beyond-worst case style analysis and show that in either case instances that are resilient to adversarial perturbations are also...
CD95/Fas ligand (CD95L) is a well characterized activator of extrinsic apoptosis. CD95L protein binds to its cognate receptor, CD95/Fas/APO-1, inducing apoptotic signaling in sensitive cells. However, expression of CD95L is toxic even in the absence of CD95. We previously reported that the CD95L open reading frame (ORF) is enriched for...
Hypnaesthesis argues for understanding somnambulism, nightmare, and insomnia as aesthetic categories in the gothic and dark romantic traditions of antebellum American literature that provide critical insights into the experiential costs of the exhortations to normative vigilance prevalent in the American Enlightenment. During this period unceasing vigilance became the watchword for...
As more thermoelectric materials/devices make it into the market for various applications, severalaspects need to be explored and optimized, beyond simply targeting high conversion efficiency at
the material levels. One critical aspect is the guarantee of mechanical stability at both the material
and the device level, which demands deeper understanding...
The leptonic and inclusive hadronic decay branching fractions of the W boson are studied using 35.9 $fb^{-1}$ of proton-proton collision data collected at $\sqrt{s}=13~TeV$ during the 2016 run of the CMS experiment. Events characterized by the production of pairs of W bosons from \ttbar and \tW processes are selected. Multiple...
Mid-infrared lasers, emitting in the spectral region of 3-12 µm that contain strong characteristic vibrational transitions of many important molecules and two atmospheric transmission windows, are highly desirable for spectroscopy sensing, infrared countermeasures, and free space communications. Previously, single-element quantum cascade lasers (QCLs) have been demonstrated with up to watt-level...
This dissertation studies the real effects of firms’ financing decisions as well as the economics consequences of bias in fair value prices of corporate bonds. The first chapter examines the impact of compliance with changes in mandated financial reporting on corporate financing and investment decisions. I employ the recent implementation...
Inflammasomes are signaling complexes that link the recognition of pathogen and danger associated molecular patterns (PAMPs and DAMPs) by cytosolic pattern-recognition receptors (PPRs) to the activation of Caspase-1, leading to the release of the pro-inflammatory cytokines interleukin (IL)-1 and IL-18, and the induction of pyroptosis. In addition to the canonical...
“Open Tables: Restaurants and Reform in Progressive Chicago” considers restaurants as contentious spaces where larger debates about gender, class, race and ethnicity, public health, and the role of the state were carried out between the end of the Civil War and the ratification of the 18th Amendment. Using Chicago as...
Proteins and many other systems are often conceptualized as networks to access analysis methods from the field of network science. Several approaches use molecular dynamics (MD) simulations of proteins to construct networks using correlational statistics. However, in the field of network science, a well-established approach for network construction is solving...
The potential association between Female Genital Mutilation (FGM) and the incidence of Human Immunodeficiency Virus (HIV) has been a part of academic discourse for three decades. By considering the mixed reports on the association between FGM and HIV so far, this dissertation contributes to the current state of research by...
This thesis explores questions in labor economics and applied microeconomics, with particular focus on issues that have implications for public policy. The first essay estimates the Frisch elasticity, sometimes known as the wage elasticity of labor supply in response to anticipated wage changes. Despite its importance in macroeconomic and public...
The commitment of resources to coaching almost always occurs in interaction with other district-wide efforts to improve instruction. Given this probable situation, it’s concerning that the field lacks the ability to provide guidance regarding how coaches might reasonably be integrated within overall plans for the coordination and improvement of instruction....
Superalloys strengthened by γ′(L12)-precipitates in γ(f.c.c.)-matrix exhibit superior high temperature mechanical properties and environmental resistance over long periods of operation, making them ideal candidates for aerospace and energy conversion applications. The emerging class of superalloys based on Co-Al-W ternary system was identified with a melting temperature 50-100 ˚C higher than...
Oxidation is an important process in synthesizing a broad range of useful products such as polymers, pharmaceuticals, and fine chemicals. While H2O2 is a highly attractive oxidant for oxidative chemistry due to its high percentage of oxygen and environmentally friendly water byproduct, it is often used in excess due to...
In knowledge-intensive work such as data analysis or emergency medicine, learning and collaboration is integral to the effective “production” process. Uncovering the mechanisms, benefits and costs of learning and collaboration is crucial for the design and operation of a successful process. My Ph.D. research centers on empirically investigating the ways...
Conceptually, we can divide this dissertation into Chapter 1 which is in the tradition of information economics and comparative statics, and Chapters 2 to 4 which had all its genesis in the same project concerning identifying the value of product differentiation to consumers with minimal assumptions, and is therefore related...
There is strong evidence for the benefits of teaching parents of toddlers with autism spectrum disorder (ASD) intervention strategies for facilitating language development. A strategy at the core of early parent-mediated interventions for ASD is responsiveness, defined as providing a child with a verbal response each time she communicates. Responsiveness...
Part I:Current approaches to synthesize π-conjugated polymers are dominated by thermally driven, transition-metal-mediated reactions. Herein we7 show that electron-deficient Grignard monomers readily polymerize under visible-light irradiation at room temperature in the absence of a catalyst. The product distribution can be tuned by the wavelength of irradiation based on the absorption...
Atomic layer deposition (ALD) is a gas-phase synthesis technique employed to manufacture thin films and metallic nanoparticles of various compositions and sizes, as well as individual, isolated species on various supports. An understanding of the dynamic surface chemistry that takes place during various ALD processes is vitally important for achieving...
In the United States, allergic disease affects approximately 60 million people and impacts more people every year. While prevalence of allergic disease has steadily increased, there has concurrently been an increase in rates of metabolic syndrome—characterized by increased abdominal girth, decreased sensitivity to insulin, and higher levels of circulating blood...
This dissertation aims to rethink how contemporary feminism might grapple with complicity, cooptation, and the concomitant failure of feminist successes through a frame other than paradox. Arguing that the paradox frame locks us into a set of “dead ends,” I shift to an orientation toward spaces between. Through sustained engagement...
The past decade has seen the rapid progress of deep learning, which becomes a game-changing technique in different data-intensive domains, with the availability of large scale data, cost-effective computing hardware and more advanced learning theory and algorithms. Despite of the rapid progress of deep learning methods in daily-life applications, such...
Cobalt(III) Schiff-base complexes (Co(III)-sb) have been utilized in the literature as antibacterial, antiviral, and inhibitory agents. Recent work has utilized their ability to displace endogenous metals from metalloproteins that exhibit aberrant gain of function pathologies in human disease. Specifically, in this dissertation Co(III)-sb has been applied as inhibitors of pathogenic...
This dissertation theorizes and examines the revival of interest in figure painting (renwuhua) in Republican China (1911–49). I argue that, in this period, figure painting assumed a central role to painters who sought to reform Chinese art, which was commonly understood as “declining.” This investigation will focus on the achievements...
This dissertation reinterprets Michel Foucault’s theory of sovereignty to offer an explanation and critique of repressive state violence. Commentators typically locate Foucault’s contribution to political thought in concepts of power that are irreducible to sovereignty or the state. In contrast, I draw on Foucault’s early genealogies of power to argue...
Understanding and controlling microbial community assembly is critical to developing novel bioprocesses for nutrient and energy recovery from wastewater and preparing for global climate change. As molecular biology tools and DNA sequencing improve, microbial ecologists can progress from answering qualitative questions about “who is there, and what are they doing?”...
SAMDI-MS (Self-Assembled Monolayers for MALDI-TOF Mass Spectrometry) couples the use of chemically-defined self-assembled monolayers of alkane thiolates on gold surfaces with MALDI-TOF mass spectrometry for rapid characterization of the surfaces. Reactions performed on the surfaces can be quantified directly by detection of the reaction substrates and products. This rapid detection...
Transnational adoption from Asia to the U.S. was institutionalized in the 1950s, when the Korean War left an estimated 100,000 Korean children orphaned or displaced. At the time, the practice was situated as a form of emergency rescue, an act of win-win humanitarianism in which average Americans could take part...
The goal of this thesis is to develop an experimental setup to evaluate and analyze the effect of crack-parallel stress on the fracture response of materials. In standard fracture test configurations, the crack-parallel normal stress is negligible. However, a new type of experiment, briefly named the gap test, revealed that...
Epigenetics is the study of chromatin-based events that regulate gene expression without the change of DNA sequence, including DNA methylation, histone modification and chromatin remodeling. Epigenetic regulators are encoded to modify chromatin in a highly regulated and dynamic manner. A growing number of studies have suggested the dysregulation of epigenetic...
Automated driving has become a very popular topic in the recent years and is becoming more and more of a reality. In this new trend, High Definition (HD) maps play an important role in many ways that will provide a safer and more efficient driving experience, especially in terms of...
Three in ten people worldwide lack access to a safely managed source of drinking water, with one in ten lacking access to a drinking water service altogether. This is projected to worsen in the coming years as climate change, infrastructure degradation, and poor governance work to further increase global water...
Understanding the regulatory programs enabling cancer stem cells (CSCs) to self-renew and drive tumorigenicity could identify new treatments. Through comparative chromatin state and gene expression analyses in CSCs vs. non-CSCs, we identified FOXK2 as a highly expressed stemness-specific transcription factor (TF). Its genetic depletion diminished stemness features and reduced tumor...
Over 6 million adults in the United States have heart failure, a serious public health problem. Differences in the progression of heart failure are in part due to variability in sex, age, and genetic variation background including ancestry. Medical biobanks provide a resource to study this variability as they include...
In this thesis, we aim to develop efficient algorithms with theoretical guarantees for noisy nonlinear optimization problems, with and without constraints, under various different assumptions. Apart from Chapter 1 which provides relevant backgrounds, the remaining of thesis is divided into four chapters. In Chapter 2, we establish the theoretical convergence...
Materials that exist as well-defined individual entities at the nanoscale typically have properties that sets them apart from their bulk form. Consequently, there has been much time and effort invested in developing new well-defined nanoscale entities, but few attempts to assemble them into bulk materials. On the other hand, there...
The retina does not act as a simple camera, rather visual information goes through multiple layers of processing before it reaches the brain. Retinal ganglion cells (RGCs) are the output neurons of the retina and process visual information in the retina and then project into the brain. There are over...
Photonics are useful in applications where high-bandwidth and low-loss interlinks are desired. One of the key components of a photonic interlink is an optoelectronic modulator which is used to encode data from an electrical signal on to an optical carrier. Many of the optoelectronic modulators typically used require integration with...
This dissertation addresses three distinct topics in development economics. The first chapter assesses the role of entry and exit in the measurement of misallocation in India. In the last decade, misallocation of productive inputs across firms has been proposed as a primary driver of differences in aggregate productivity over time...
Mechanosensation is an essential behavior for cellular health that depends on the interactions between the plasma membrane and stretch-activated ion channels. To date, a few studies have measured the effect of membrane composition on protein behaviors from folding to function. However, the relationship between membrane mechanical properties and these behaviors...
Cholinergic modulation of the brain cortex is critical for cognitive processes, and altered cholinergic modulation of the prefrontal cortex is emerging as an important mechanism of neuropathic pain. Despite the known sex differences in pain prevalence and perception, the precise nature of the mechanisms responsible for sexual dimorphism in chronic...
Meiosis is a highly regulated process necessary for proper chromosome division. Zincfluxes regulate mammalian meiosis; between prophase I and metaphase II, total intracellular zinc
increases by 50%, while 20% of zinc is released in “zinc sparks” following fertilization. Although
zinc fluxes had been shown to be conserved in mammals, it...
Found in 1-2% of the population, bicuspid aortic valve (BAV) is the most common congenital cardiovascular disease and is associated with increased risk of aortic valve dysfunction and aortic disease. Current treatment is focused on surgical intervention either after the development of symptomatic aortic stenosis/regurgitation or aortic diameter thresholds. However,...
While metabolic engineering can enable the sustainable bioproduction of new materials, efforts are often impeded by pathway bottlenecks. To mitigate the effects of toxic or reactive intermediates and resource competition resulting from heterologous pathway incorporation, bacterial microcompartments (MCPs) have recently been considered for engineered compartmentalization in bacterial host organisms. MCPs...
Melanin is a functional biopolymer most commonly associated with human skin pigmentation, where it serves as a radiation protection agent, shielding us from the harmful effects of UV radiation. However, melanin is also present in human ears, eyes, hair, and brains, serving a variety of functions. In fact, melanin...
Transcription plays a pivotal role in the transfer of genetic information within living organisms. It serves as the initial step in gene expression, allowing cells to convert the instructions encoded in their DNA into functional molecules. Eukaryotic transcription initiation is a complex and dynamic process that requires joint efforts from...
Western scientific norms (e.g., Bacon, 1623/2005) dictate that mechanistic explanations like “rain falls because clouds form water vapor” are preferable to teleological ones like “rain falls so that plants should grow. Do people have preferences that naturally align with this? The predominant interpretation of past research is that they do...
Uranium is a unique, multifaceted element that possesses rich chemistry and promise for challenging reactions. Pressing demands within nuclear stockpile stewardship and the nuclear energy sector call for development of this relatively understudied element. Uranium metal–organic frameworks (U-MOFs), a class of nanoscale hybrid materials, harness the exceptional attributes of uranium...
With the increasing demand for customized products, rapid prototyping, and small-batch production, incremental sheet forming (ISF) is gaining ever-growing attention. The potential of ISF to produce parts without the use of geometry-specific dies has revolutionized the sheet forming processes. Despite its promising characteristics, ISF thus far has not been extensively...
Commonsense inference is a critical capability of modern artificial intelligence (AI) systems. The machines need commonsense knowledge to perform tasks exactly like human being does. Learning commonsense inference from text has been a long standing challenge in the field of natural language processing due to reporting bias -- people do...
This dissertation aims to: 1) characterize the range of beliefs museum practitioners have about racial, ethnic, and cultural diversity; 2) their understanding of the role of race, culture, and ethnicity in minoritized learners’ sensemaking; and 3) the areas of tension and symmetry between practitioners’ values and their perception of their...
How do perceivers stereotype people who are at the margins of multiple, interlocking social identities? The present dissertation proposes and tests a model of intersectional stereotyping called intersectional categorization theory (ICT). This model advocates the following core ideas: (a) that perceivers use one lens at a time for making sense...
Understanding associative memory is fundamental for a variety of neurological and neurodegenerative diseases, however, a large proportion of this research has excluded female subjects due to unsubstantiated bias. By including intact females, ovariectomized females and males in the study of associative memory, clear sex differences in acquisition emerged. Female mice...
The concept of epistemic infringement marks a novel entry into the social epistemology literature concerning epistemic misconduct. Epistemic infringement constitutively involves the systematic contravention of social and epistemic norms, particularly in a manner that serves to erode epistemic agency. This dissertation identifies epistemic infringement as a useful theoretical tool for...
Travel time is a key aspect of capturing and evaluating the operational performance and service quality of transportation systems, and travel time improvement is a common objective for travelers, service providers, transportation practitioners and agencies. However, the reliability of travel times, including the probability of unexpected delays, is an important...
Self-Assembled Monolayers for MALDI-TOF Mass Spectrometry (SAMDI-MS) is a technique that combines self-assembling molecules of alkane disulfides on gold and MALDI-TOF mass spectrometry. By using well-defined monolayers with functionalizations that both prevent non-specific adsorption onto the surface and presents immobilization handles, it is possible to pull out analytes of interest,...
Human language processing is incremental. In this dissertation, I explore how an incremental perspective can help us clarify our understanding of transformational syntax, which typically proceeds bottom-up. As part of our exploration, I develop an incremental head-driven parsing algorithm for Minimalist Grammars. The two main innovations of this parsing algorithm...
Membrane contact sites (MCSs) facilitate communication and organization of organelles that contribute to fundamental cellular processes. It has become increasingly appreciated how extensive and essential MCSs are for cellular health, and this field is rapidly growing. We use budding yeast as a model system to study the mechanisms of how...
Chemokines, such as Stromal Derived Factor 1 (SDF-1 or CXCL12) and their G protein coupled receptors (GPCRs) are well known regulators of the development and functions of numerous tissues. CXCL12 has two receptors: CXCR4 and CXCR7 or atypical chemokine receptor 3 (ACKR3). CXCR7 has been described as an atypical “biased”...
We have a remarkable ability to perform complex, coordinated movements without much conscious effort. In addition to the computations required to generate commands for muscles, a key aspect of coordinated motor control is incorporating sensory feedback about the movement. One of the most important feedback routes is through proprioception, the...
Uttering Sonic Dominicanidad: Women and Queer Performers of Música Urbana Verónica Dávila Ellis What meanings are ascribed to the voices and sonic compositions of Caribbean and Latinx women and queer performers? What do their sounds tell us about Caribbean identity, gender, sexuality, and race? This dissertation centers the work of...
This dissertation considers how women’s spectatorship—how women are imagined as viewing subjects, and what are defined as feminine ways of watching—is transformed by digital technologies, and what it reveals about the shifting nature of privacy and visibility. It maps the contours of our current configuration of gendered looking relations by...
Gastrointestinal (GI) colonization by Klebsiella pneumoniae is a risk factor for subsequent infection as well as transmission to other patients. Additionally, colonization is achieved by many strain types that exhibit high diversity in genetic content. However, how K. pneumoniae achieves colonization and whether the genetic factors it uses differ by...
Machine learning is seeping into every fabric in various practical domains such as autonomous driving, wearable computing, and smart buildings. However, in the actual development and integration, especially when the learning-based components are frequently included as components of large complex systems where the physical instances can be included as interactable...
As polymer science has advanced as a field, so too have the uses for polymeric materials. We encounter polymers and plastics on a daily basis, and while their presence has greatly improved our quality of life, they have also had a profound and often negative impact on our environment. Plastic...
Electrostatic interactions mediated by ionic environments play a central role in physical processes across materials science, chemistry and biology. Key biological phenomena, such as the condensation and packaging of DNA, ion transport across cellular membranes and the enzymatic action of proteins, rely on the complex interplay between nanoscale electrostatic, osmotic...
Standard-based accountability policies have profoundly shaped the landscape of public education in the United States. At the heart of these policies are standardized assessments, administered annually, which are used to evaluate schools and, at times, teachers. While always controversial, opposition to these policies increased following the widespread adoption of the...
Superconductivity is a fascinating manifestation of quantum mechanics on a macroscopic scale that has led to greater insights of the strongly correlated physics of a large number of interacting electrons ever since its discovery $\sim$ 100 years ago in elemental Hg. The unconventional superconductors that are based on uranium offer...
This dissertation presents research on the game theory of political power, both between and within nations. It first revisits a classical distinction between three different types of power or influence: information, rewards and threats. By presenting a binary-action Principal-Agent problem which incorporates the essential ingredients of all three types of...
The term blowback originated from the American intelligence community to indicate the unexpected consequences of American foreign policy. In my dissertation, I give an account of how blowback results from these security policies. Blowback shows the cases that security policies create more harm than good to the enacting country due...
At its core, the purpose of microscopy is to make objects and their underlying structures visible under high magnification. With the remarkable progress of electron microscopy, the sub-micron “high” magnification of light microscopy has been completely refashioned to encompass subatomic length scales. Unfortunately, higher-magnification does little to negate existing interpretability...
Plasmonic nanoparticles have very large absorption cross sections and can concentrate the local density of photon states on the nano scale. When they are coupled to molecules or semiconductor nanocrystals and form different hybrid nanostructures, various light-matter interaction processes can be significantly enhanced or manipulated, including optical responses like fluorescence...
With the global rise of surveillance technology, contentious episodes may be captured on video from multiple perspectives. These perspectives include the third-person visual perspective such as red-light cameras and dashboard cameras, the first-person visual perspective such as body-worn cameras, and perspectives from written descriptions such as police reports and witness...
This research especially helps for the design of concrete structures which has to last at least for 100 years such as bridges. The research aims to give a better prediction of long-term deformations of concrete and improve the structure design based on these predictions. The accurate prediction helps in capturing...
Mission-critical systems are those imperative systems whose failures can result in catastrophic consequences. Traditional techniques, such as manual investigation and testing, cannot ensure the absence of errors and security vulnerabilities within these systems. This dissertation leverages formal methods to comprehensively examine several mission-critical systems and their essential components. For each...
The ability to regenerate lost tissues or organs is widespread in the animal kingdom, but the mechanistic basis underpinning this process is incompletely understood. The planarian flatworm Schmidtea mediterranea has an incredibly robust and flexible capacity for regeneration, able to regenerate an entire organism from arbitrary starting points. This makes...
Exploratory phase stability analysis in Materials Science has two primary goals: (a) Characterizing the evolution of the materials single phase field in composition space to identify solubility and electronic dopability limits and (b) Accelerated prediction of new phases of technological importance. In this thesis we reorganize defect theory --- the...