Advances in biosensor engineering have enabled the design of programmable molecular systems to detect a range of pathogens, nucleic acids, and chemicals. Here, we engineer and field-test a biosensor for fluoride, a major groundwater contaminant of global concern. The sensor consists of a cell-free system containing a DNA template that...
From 2008 to 2019, a range of new interactive and immersive digital formats that present new possibilities for musical and artistic expression have become available. In order to begin the work of uncovering what new compositional and experiential possibilities are now possible, this document will examine each format’s core concepts...
The saxophone has long been an instrument at the forefront of new music. Since its invention, supporters of the saxophone have tirelessly pushed to create a repertoire, which has resulted today in an impressive body of work for the yet relatively new instrument. The saxophone has found itself on...
Metabolic conditions affect the developmental tempo of most animal species. Consequently, developmental gene regulatory networks (GRNs) must faithfully adjust their dynamics to a variable time scale. We find evidence that weak repressors of gene expression provide the necessary coupling between GRN output and cellular metabolism. Using a mathematical model that...
Recent advances in cell-free gene expression (CFE) systems have enabled their use for a host of synthetic biology applications, particularly for rapid prototyping of genetic circuits and biosensors. Despite the proliferation of cell-free protein synthesis platforms, the large number of currently existing protocols for making CFE extracts muddles the collective...
In 1936 Modibo Keita, a twenty-year-old student at the distinguished Ecole William Ponty in Gorée, Senegal, wrote his “mémoire de fin d'étude” on Soninke childhood. The original manuscript is held in the archives of French West Africa in Dakar, part of the collection of “cahiers de William Ponty.” This paper... and En 1936 Modibo Keita, un étudiant de vingt ans à l'école distingué William Ponty à Gorée, au Sénégal, a écrit son mémoire de fin d'étude sur l’enfance sarakollé. Le manuscrit original se trouve dans les archives de l'Afrique occidentale française à Dakar, où il fait partie de la collection de...
This study explored the mentoring experiences of doctoral students in science, technology, engineering, and mathematics (STEM) doctoral degree programs at Northwestern University. Research suggests that mentoring relationships support student success in STEM disciplines, and further, that lack of mentorship may be a barrier for female students. A mixed-methods approach employing...
In the Western classical art music tradition, a high level of music performance is achieved at the intersection of a musician's emotional, cognitive, and physical processes. Expert classical musicians have both an aural imagining of the sound they intend to produce and the physical associations of what it feels like...